Klaus Tschira Boost Fund
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Contact
Dr. Birte Seffert (she/her)
GSO e. V.
Friedrichstrasse 60
10117 Berlin
Phone: +49 (0) 30 2067 9967
ktboost(at)gsonet.org
Application
We now welcome applications for the 8th KT Boost Fund.
Applications must be uploaded via GSO’s online application form.
The application deadline is October 1, 2026, 23:59 CEST.
Idea
Through the Klaus Tschira Boost Fund, we promote excellent researchers by providing
- flexible funding for independent, explorative, risky, and interdisciplinary projects;
- support in building (international) collaborations and networks;
- targeted workshops, coaching, and peer support on professional and personal development.
The Boost Fund gives postdoctoral researchers greater flexibility in shaping their career paths, accelerating their careers, and promoting early independence.
The Klaus Tschira Boost Fund was developed by GSO – Guidance, Skills & Opportunities for Researchers e.V., which manages the program and is the main contact for fellows and alumni. The Klaus Tschira Stiftung generously provides funding.
Additional Resources
On July 8, 2026, at 4:00 PM (CEST), we will host our Info Webinar, “How to Apply for the Boost Fund 2026/27“. We will record the webinar and post the recording along with the slides here. Register for the webinar
Be sure to also visit our career resources website where you find tips from Boost alumni on writing grant applications, the first articles in the new “Keeping Up with the Boost Fellows” series, and all previous installments of the series.
Program Information
We fund 15 new fellows. Projects can start between May 1 and Oct. 1, 2027.
It is possible to apply for funding of up to € 115,000 for a period of up to 24 months. Funding can be used for all types of costs, but no more than € 67,000 gross for the fellow’s salary for the duration of the project. Junior group leaders or junior professors cannot apply for funding for their own position.
Fellows profit from a 4-part career development workshop series on
- Linking Purpose and Career (6h in-person workshop in June 2027),
- Being an Effective Manager,
- Practicing Self-Care and,
- Assessing your Capacity to Lead (each 3,5h online, one session per month),
get free access to GSO’s career advice & coaching services, and become members of an exclusive alumni network.
If the application is successful,
- the fellow and host institution agree to the Conditions of Grant Approval (see download section), and
- we expect the fellow to attend the Welcome Event for all fellows & alumni in June 2027 in Berlin, and the 4-part career development workshop series
Funding must be requested by the institution and made freely available to the fellow. All funding must be used as in the submitted and approved budget plan. All expenses must be documented in a yearly use of funds (Verwendungsnachweis) to be submitted to GSO.
There is no legal entitlement to funding. Funding is subject to the availability of funds from the Klaus Tschira Stiftung.
The program addresses postdoctoral researchers who
- are employed at a state-funded (public law) university or state-funded (public law) university of applied sciences (= öffentlich-rechtliche Universität oder HAW), at a Bundesamt or Bundesanstalt (Ressortforschung), at a Fraunhofer, Leibniz, Max Planck, Helmholtz, or DLR institute or at EMBL in Germany at the latest at the start of your project,
- conduct non-clinical research in one or more of the following areas: Biology, Chemistry, Computer Science, Geosciences, Mathematics, Neurosciences and Physics,
- do not yet have a permanent position or tenure option,
- and do not have acquired further substantial funding (see pdf Program Information for details).
We now welcome applications for the 8th KT Boost Fund.
Applications must be uploaded via GSO’s online application form.
The application deadline is October 1, 2026, 23:59 CEST.
Our Fellows & Alumni
Thanks to the generous funding of the Klaus Tschira Stiftung, we have so far been able to support 90 fellows in their research and academic independence in seven cohorts.
Alexander Gräwe
Annika Burmester
Eliza Loo
Evangelia Christodoulou
Jens Boos
Julia-Maria Hübner
Lars Longwitz
Maria Jose Perez Jimenez
Maria Francesca Viola
Ping Shen
Roxana Zeraati
Sara E. Anthony
Shyan Akmal
Yannick Becker
Yeliz Unutulmazsoy
Alexander Gräwe
#Synthetic Biology
#Living Therapeutics
#Biocontainment
Project Idea
What if we could program microbes to fight disease? While infections caused by harmful microbes can cause rapid health decline, beneficial microbes help to keep us healthy. One new strategy to fight harmful microbes is to genetically modify beneficial microbes to act as living therapeutics. However, we must first establish responsible approaches to ensure their safety. We will use synthetic biology to build a “TheraSafe” microbe that combines pathogen-countering abilities with built-in biosafety mechanisms, guiding the future development of safe and effective living therapeutics.
How does the KT Boost Fund support you and your project idea?
Currently, the biosafety implications of potentially therapeutic GMOs are not adequately addressed. The KT Boost Fund will enable me to supervise a PhD candidate, allowing us to set up, test and verify innovative biosafety concepts. As a supervisor of a PhD candidate, I will be able to demonstrate my independence and readiness to take on responsibility when applying for more senior academic positions in the future. I appreciate that the KT Boost Fund offers dedicated workshops and 1-on-1 counselling sessions that will provide me with the necessary skills for this personal development.
If I had more time for things other than research, I …
…would visit more symphony concerts, compose more music for smaller ensembles and join an a cappella choir. Like science, music has the power to make the world a better place.
Profile
Name: Alexander Gräwe
Research field: Synthetic & Infection Biology
Institution: Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (Leibniz-HKI), Department of Molecular and Applied Microbiology
More about me
#Multiple zeta values
#Modular forms
#Algebraic structures
Project Idea
I investigate connections between multiple zeta values and modular forms, which both appear in many areas of mathematics and physics. Multiple zeta values are special numbers defined by infinite sums – for example, classical Riemann zeta values are defined by sums such as 1 + 1/2² + 1/3² + … . Modular forms are highly symmetric functions that encode deep arithmetic information about their coefficients. By studying objects that combine characteristic features of multiple zeta values and modular forms, the aim is to uncover new arithmetic properties and shared algebraic structures.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund enables me to deepen my network with the European community working on modular forms and the Japanese community working on multiple zeta values through research visits, workshops, and conferences. It provides the time needed to focus on my research, advance ongoing projects, and establish my profile as an independent researcher while exploring new directions. It also provides access to mentoring and career development programs.
If I had more time for things other than research, I …
…would spend more time enjoying sports, especially playing softball and going for runs. I would also dedicate more time to improving my Japanese language.
Profile
Name: Annika Burmester
Research field: Mathematics
Institution: Bielefeld University
More about me
#Root microbiota
#Microbial interaction
#Microbiota engineering
Project Idea
In nature, plants coexist with microbes including those that benefit plants by supplying nutrients, protecting against pathogens, and boosting growth. Scientists aim to use these beneficial microbes as bioinoculants to improve crop performance, but success is limited by our limited understanding of how these bioinoculants integrate with existing microbes. This project will map root microbes and their metabolic activity to build interaction networks that predict microbial integration, thereby advancing smarter rhizobiome engineering and bioinoculant design.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund will transform my career by enabling high-impact research outputs and strengthening my competitiveness for future funding. It will demonstrate my independence and support my transition into a leadership position. The project will lay the foundation for an independent research group, generate high-impact publications, increase visibility, and expand academic and industry collaborations. The KT Boost Fund helps positioning me as an emerging player in my field.
If I had more time for things other than research, I …
…would enjoy sipping a glass of (good) wine with a fiction in my hand. On other days, I enjoy understanding the science behind producing a perfect loaf of bread.
Profile
Name: Eliza Loo
Research field: Plant Biology
Institution: Heinrich Heine University Düsseldorf, Institute for Molecular Physiology
More about me
Evangelia Christodoulou
#Foundation models
#Sample size requirements
#Medical image analysis
Project Idea
AI can help doctors read medical images like X-rays or MRIs, but developing these systems usually needs lots of labeled images. New “foundation models” already understand many visual patterns and may need less data to adapt to medical tasks. However, one big question remains: how much data is enough? This project will introduce an adaptive way to estimate how much data different medical AI tasks require, together with an open-source tool for data requirement estimation. The goal is to help researchers build reliable AI that can safely support doctors in clinical practice.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund would enable me to pursue an ambitious and often overlooked research question: how much data is truly needed to reliably adapt modern AI models for medical imaging. The funding will support systematic experiments, enable the involvement of student researchers, and facilitate the development of open tools for the research community. Equally important, the program will foster my growth as an independent scientist, helping me build collaborations and shape my own research direction in trustworthy medical AI.
If I had more time for things other than research, I …
…would dive even deeper into cinema as a devoted cinephile, keep exploring my meticulous lists of food and coffee spots during my travels, and wander through contemporary art spaces.
Profile
Name: Evangelia Christodoulou
Research field: AI Validation in Medical Imaging
Institution: German Cancer Research Center (DKFZ), Division of Intelligent Medical Systems
More about me
#Black holes
#Dark matter
#Gravitation
Project Idea
Our universe is not just made of ordinary everyday matter (electrons, protons, neutrons), but also contains dark matter (an invisible form of matter that does not emit light). In my project, I want to model dark matter as a combination of particles and black holes. This idea has faced significant challenges in the past, but I believe that a joint approach between the gravity and particle physics community can uncover feasible scenarios that have not yet been studied in detail, and potentially change the way we think about dark matter and the constituents of our universe.
How does the KT Boost Fund support you and your project idea?
My work on black hole/particle composite dark matter is situated at the interface between gravitational physics and particle physics, and crucially depends on input from both disciplines. It is explorative in nature, and currently not represented as one of my host institution’s permanent research foci, and therefore it is difficult to obtain funding for this type of work. The KT Boost Fund allows me and my group members to establish connections between the research fields, and perform a first viability study, which would otherwise not be possible.
If I had more time for things other than research, I …
…would spend more time in my electronics corner at home, where I work on projects and video tutorials that I post on my YouTube channel FriendlyWire; take up ballroom dancing with my wife again; play more piano.
Profile
Name: Jens Boos
Research field: Black Hole Phenomenology
Institution: Karlsruhe Institute of Technology, Institute for Theoretical Physics, Department of Physics
More about me
#Battery Recycling
#Ionometallurgy
#Metal Recovery
Project Idea
Lithium-ion batteries power our world, but they contain valuable metals, the mining of which harms the environment and often involves poor social conditions. Current recycling methods are energy-intensive and unsustainable. Our project develops a greener approach using ionic liquids – special salts that dissolve metals at low temperatures and enable metal recovery using electricity. Based on the natural by-product of sugar-beet production, betaine, these ionic liquids avoid environmentally harmful fluorine-containing ingredients, creating a low-waste process that supports a circular economy.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund will be transformative for my professional and personal growth, enabling me to expand my expertise and direct my research toward a topic I am deeply passionate about: sustainable chemistry and materials circularity. With this support, I can build the foundation for an independent academic career while addressing urgent global challenges. The fellowship’s unique focus on training and networking will further equip me to lead a research group and mentor the next generation of scientists, ensuring my work has lasting scientific and societal impact.
If I had more time for things other than research, I …
…would spend more time on archery, reading literature classics from around the world, exploring nature, and, most importantly, enjoying time with family and friends.
Profile
Name: Julia-Maria Hübner
Research field: Chemistry
Institution: Dresden University of Technology, Faculty of Chemistry and Food Chemistry, Inorganic Chemistry II
More about me
#Organocatalysis
#Green Chemistry
#Chirality
Project Idea
The enzymes in your body, the cellulose in a tree and every (bigger) molecule in nature are all “chiral”. Chirality is a property that does not influence the physical properties of a molecule (like melting point or color), but its properties when interacting with other chiral molecules (like receptors in your body). We want to find new sustainable ways to make chiral compounds, specifically phosphorus containing organic molecules called phosphanes. We use metal-free organocatalysis and convert waste from industry to make chiral phosphanes. These phosphanes are very useful to make chirals drugs.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund allows me to put my research own ideas into reality. I want to initiate my research line focused on the development of sustainable methods on the interface of organic chemistry and biochemistry. The KT Boost Fund will help me by giving me access to chemicals and specialty glassware needed to develop new catalytic methods and start my own research group. I will also be able to mentor a researcher with the funding of the KT Boost Fund to accelerate the experiments towards the development of more sustainable methods.
If I had more time for things other than research, I …
…would travel around to do more escape rooms; always a good time with friends, solving puzzles and racing against the clock.
Profile
Name: Lars Longwitz
Research field: Organic Chemistry
Institution: University of Hamburg, Institute of Organic Chemistry
More about me
Maria Jose Perez Jimenez
#Neuroendocrinology
#Epigenomics
#Women’s Brain Health
Project Idea
Why do women’s brains experience aging differently? A major factor is the shift in hormones like estrogen. My research uses human stem cell models to map how these hormones keep brain cells healthy and resilient. By studying how metabolism and genetics interact during hormonal changes, I want to identify the biological pathways that keep the brain sharp as we age. This research focuses specifically on female-specific mechanisms that have been overlooked for too long. My goal is to uncover the secrets of brain protection to ensure women live healthier, more independent lives.
How does the KT Boost Fund support you and your project idea?
For too long, the link between metabolism and hormones in the aging brain has been overlooked. The KT Boost Fund lets me bridge my background in neuroscience and metabolism with epigenetics. This multi-omic approach is risky and explorative, but it is the only way to find the biological pathways that keep the female brain resilient. Without this support, the root causes of why women’s brains age differently would remain unmapped. This funding is critical for my mission to build a research program dedicated to uncovering the biological mechanisms that protect women’s brain health.
If I had more time for things other than research, I …
…would spend it outdoors with my family, traveling and exploring new cultures. I would also work on creative projects like painting, pottery, and knitting.
Profile
Name: Maria Jose Perez Jimenez
Research field: Metabolic and Epigenetic Neuroscience
Institution: Max Planck Institute for Immunobiology and Epigenetics, Department of Chromatin Regulation
More about me
#Maternal obesity
#Neurodevelopment
#Macrophage
Project Idea
Our health in adulthood can be shaped before we are even born. My project asks whether a mother’s health and diet during pregnancy can change how a baby’s immune cells develop in the gut. These immune cells are important for many things, but they also help control the “mini-brain” in our gut. I will test how a mother’s diet and gut bacteria influence these cells, and whether specific bacterial products can alter gut development and increase the risk of disease later in life. Understanding this could help us find new ways to prevent digestive diseases before they begin.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund will support me at a pivotal stage as I prepare for independence. It will give me the time, resources, and training to build my own research direction with dedicated student support. With less day-to-day technical pressure, I will be able to focus more on mentorship, thoughtful project planning, and growing as a leader. The fund will also enable conference travel and open access publishing, helping me build lasting international collaborations for the future.
If I had more time for things other than research, I …
…would spend more time hiking in the mountains! I also would love to spend more time with my family and friends. And finally finish that jumper I’ve been knitting…
Profile
Name: Maria Francesca Viola
Research field: Immunology
Institution: University of Bonn, LIMES Institute, Developmental Biology of the Immune System
More about me
Ping Shen
#Osteoarthritis
#Adaptive immunity
#T cells
Project Idea
Osteoarthritis is a severe long-term joint disease affecting millions of people worldwide, with no cure. Influenced by the paradigm that it is a “wear and tear” condition, the role of lymphocytes in osteoarthritis has been largely overlooked. We found that lymphocytes played a critical role during its development, since mice had no lymphocytes were protected from age-related osteoarthritis. We also found that T cells of osteoarthritis patient exhibited joint tissue–exclusive T cell clonal expansion, a hallmark of adaptive immunity. This project is to understand how T cell–mediated adaptive immune responses contribute to osteoarthritis development.
How does the KT Boost Fund support you and your project idea?
My career goal is to lead a research group studying the interplay between immunity and osteoarthritis and to pursue a professorship. The flexible and promoting nature of the KT Boost Fund would enable me to generate pivotal data, lead high-impact publications, and strengthen my competitiveness for major grants such as the ERC and DFG proposals. Without this important support, I would not be able to redefine osteoarthritis as an immune-mediated disease, open new directions in osteoarthritis research, nor pursue my path towards a professorship.
If I had more time for things other than research, I …
…would teach my kids Chinese so they can read original novels and have fun. I would train regularly in table tennis and compete for my club.
Profile
Name: Ping Shen
Research field: Osteoarthritis & Immunology
Institution: Charité – Universitätsmedizin Berlin (CCM), Department of Rheumatology and Clinical Immunology; German Rheumatology Research Center (DRFZ), Pitzer Laboratory of Osteoarthritis Research
More about me
#Foraging
#Timescales
#Reinforcement learning
Project Idea
To survive in ever-changing environments, humans and other animals must adapt their decisions to the environmental dynamics. In this project, we will use foraging behavior as a window into naturalistic decision processes to investigate the mechanisms underlying this adaptivity. We will combine computational models and theory-driven experiments in humans to uncover how they learn about their environmental dynamics during foraging and adapt their decisions accordingly. Our results will reveal how interactions between brain, behavior, and environment drive adaptive decision-making.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund will provide an exceptional opportunity to advance my academic career by accelerating my path toward independence. Specifically, it will allow me to take the first decisive step toward establishing an interdisciplinary research program to uncover the mechanisms of adaptive behavior, a core component of biological intelligence. Moreover, it will support the development of the leadership and professional skills needed to build my own research group in the future to foster a supportive and effective research environment.
If I had more time for things other than research, I …
…would read more fiction, travel the world, and engage more in communicating science to the public.
Profile
Name: Roxana Zeraati
Research field: Neuroscience
Institution: Max Planck Institue for Biological Cybernetics
More about me
#Methylotrophic methanogenesis
#Stable isotopes
#Methane cycling
Project Idea
Stable isotopes can help to understand pathways of production and consumption of the important greenhouse gas methane in the environment. Existing work has focused on two specific microbial pathways of methane production and on methane oxidation. A third pathway of methane production from methyl compounds has received little attention, in particular with regard to its effect on stable isotopic composition of methane. With support from the KT Boost Fund, I will be able to track stable Carbon and Hydrogen isotopic composition of methane using a novel, laser-based dual isotope monitoring instrument.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund enables me to pursue further education in stable isotope analysis and applications, as well as helping to support my establishment as an expert in stable isotope biogeochemistry and microbial ecology of methane cycling. It would also give me a boost in the field of studying methylotrophic methanogens, which is a personal interest of mine, and a hot topic in the field of methane cycling. The funding gives me stability while I look for additional funding to stay within my current working group in which I have the tools and support to develop my research interests and career.
If I had more time for things other than research, I …
…would spend more time traveling, in an environmentally friendly manner which always takes time. I would take more ceramics courses and attend more yoga courses. I would also like to adopt a dog.
Profile
Name: Sara E. Anthony
Research field: Biogeochemistry & Microbial Ecology
Institution: University of Münster, Institute of Landscape Ecology, Ecohydrology and Biogeochemistry Research Group
More about me
#Subgraph detection
#Graph decomposition
#Erdős-Hajnal conjecture
Project Idea
Modern science is driven by finding patterns in data. My project is about designing better algorithms for finding patterns in graphs, a type of object used to model many different kinds of data, ranging from relationships in social networks to reaction pathways in chemistry. I plan to construct these new algorithms by connecting techniques in computer science with theorems from pure mathematics.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund grants me access to travel funds that will help me visit researchers at other universities studying graph algorithms, invite experts in structural graph theory to work with me in Germany, and give talks at other institutions on my research. In this way, the fund will help foster the deep collaborations necessary for success in a project like mine, which involves communication between different communities in math and computer science.
If I had more time for things other than research, I …
…would read more stories, write more stories, play more board games, create new board games, spend more time with family, learn more math (for fun, not research), and visit El Ateneo Grand Splendid.
Profile
Name: Shyan Akmal
Research field: Computer Science
Institution: Max Planck Institute for Informatics, Algorithms and Complexity
More about me
Yannick Becker
#Language evolution
#Development
#Gestures
Project Idea
How language evolved is one of the big questions in science. Both phylogenetic (through primate comparisons) and ontogenetic (developmental) approaches can be fruitful. My previous research with newborn baboons revealed that the lateralisation of brain areas for language predicts which hand the monkeys will use to communicate later in life. Transposing that knowledge to human infants, this project now investigates whether brain lateralisation for language initially develops for communicative gestures in infants who do not speak yet. This might affect how they learn to speak later on.
How does the KT Boost Fund support you and your project idea?
In this KT Boost Fund, I’m attempting an unusual goal: applying insights from monkey research to human development. What can monkeys teach us about language development? Through this, I aim to better understand language development and step beyond my current field to become a group leader soon. The KT Boost Fund is a unique stepping stone that will help me to: 1) open myself up to the new field of human development, 2) establish an independent research agenda and emancipate myself from my supervisors, 3) become financially independent, and 4) acquire leadership and management skills.
If I had more time for things other than research, I …
…would finally have my punk band and would be running wild across the country.
Profile
Name: Yannick Becker
Research field: Language & Brain Evolution
Institution: Max Planck Institute for Human Cognitive and Brain Sciences, Lise Meitner Research Group Cognitive Neurogenetics
More about me
#Hydrogen barrier layers
#Thin film design by PVD
#Hydrogen–surface interactions
Project Idea
Hydrogen molecules are extremely small, and they can leak through many materials. Preventing leakage during storage and transport is a major challenge for a clean hydrogen economy aiming to reach Net-Zero CO₂ emissions by 2050, and durable barrier materials are urgently needed. We will develop chemically complex ceramic coatings with carefully designed tiny internal structures that block hydrogen. By understanding how structure at nanoscale controls performance, we aim to design longer-lasting, safer, and more efficient barriers, helping power the hydrogen economy and advance materials science.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund is decisive at this critical stage of my career, as unlike classical funding schemes, it allows me to bridge my existing expertise in thin-film design with hydrogen–surface interactions, developing an original and societally relevant research direction. The funding will help me establish the foundation for my research in hydrogen–materials interactions, enabling me to extend beyond the scope of this project. Equally important, the funding provides access to mentoring and opportunities to engage with outstanding fellows, shaping both my research and career trajectory.
If I had more time for things other than research, I …
…would walk the 500 km Lycian Way, learn Italian, teach on different topics after learning, and spend more quiet time with my family while enjoying nature.
Profile
Name: Yeliz Unutulmazsoy
Research field: Thin film design by PVD methods, plasma–surface interactions, materials characterization, hydrogen barrier materials
Institution: Leibniz Institute of Surface Engineering / Barrier & Precision Coatings
More about me
Cipriana Anghel-Stan
Yitzchak Ben Mocha
Tamir Eliav
Florian Hubrich
Pascal Hunziker
Björn Klaes
Anthodesmi Krontira
Sanne Maas
Katrina Meyer
Mirja Mittermaier
Mariia Nesterkina
Jan Pennekamp
Felix Sauer
Sam Thiele
Timothy Warwick
#Dirac operators
#Degenerating covering spaces
#Heat kernel asymptotics
Project Idea
We consider a compact Riemannian surface X, for example, the surface of a donut. A geodesic on X is a curve which minimizes the distance between any two close points which lie on it. We choose such a simple closed curve and gradually pinch it, making its length shrink to zero. We add another “layer” over X, an infinite normal covering space, and proceed to pinch all the preimages of our geodesic in this upper space. Our aim is to study the “music” generated during this process, which can be described mathematically by the von Neumann trace of the Dirac operator acting on the covering space.
How does the KT Boost Fund support you and your project idea?
The Klaus Tschira Boost fund will give me independence. It will provide me with the necessary time to develop new mathematical tools and work on the riskier projects described in my research proposal. It will give me the opportunity to travel for research visits in Germany and abroad, promoting my work in mathematical events while meeting new collaborators, as well as organizing a tailored conference to bring together the latest advances in the topics which passionate me.
If I had more time for things other than research, I …
…would plan more hiking and mountain biking trips with my friends, restart writing on my personal blog about these adventures, and I would play the piano more often.
Profile
Name: Cipriana Anghel-Stan
Research field: Mathematics
Institution: University of Göttingen, Institute of Mathematics
More about me
#Ethology
#Cooperative breeding
#Reliable Data
Project Idea
Why do some bird and mammal species (including humans) help to raise the offspring of their other group members?
The Cooperative-Breeding Database (Co-BreeD) project provides the research community with a state-of-the-art data about different forms of alloparental care (e.g. nursing by non-mothers, carrying of infants by a neighbour) in hundreds of species. Collaboration with dozens of international researchers secures fair acknowledgement, data reliability & publication of important natural history data (including from nowadays modified habitats).
How does the KT Boost Fund support you and your project idea?
The Klaus Tschira Boost Fund funding enables the Cooperative-Breeding Database (Co-BreeD) to realise its three main goals simultaneously :
1) Curating high-quality data on alloparental care in birds and mammals
2) Establishing an updateable, open access and fair database
3) Test hypotheses about the causes and consequences of alloparental care
If I had more time for things other than research, I …
…would swim, travel the world (with/out my kids), promote environmental conservation.
Profile
Name: Yitzchak Ben Mocha
Research field: Ethology
Institution: University of Konstanz, Centre for the Advanced Study of Collective Behaviour
More about me
Personal website
Bluesky (personal)
Bluesky (Co-BreeD project)
Tamir Eliav
#Sleep
#Learning
#Songbird
Project Idea
How does sleep help us learn new skills? Just like humans, young songbirds learn to sing by imitating others, and sleep plays a key role in refining their songs. However, the brain processes behind this are still a mystery. By studying the sleeping brain of young birds, this project aims to uncover how sleep shapes learning, offering new insights into how our own brains consolidate skills and memories overnight.
How does the KT Boost Fund support you and your project idea?
The Klaus Tschira Boost Fund allows me to implement cutting-edge high-density neural recording technologies in freely behaving songbirds, enabling continuous 24/7 monitoring of sleep and learning dynamics in a natural setting. Additionally, it supports international collaborations and professional growth—both essential for developing my independent research direction and taking the next step toward establishing my own lab.
If I had more time for things other than research, I …
…would go on more outdoor adventures with my kids, play the guitar, and learn a new instrument.
Profile
Name: Tamir Eliav
Research field: Computational and Systems Neuroscience / Neuroethology
Institution: Max Planck Institute for Biological Intelligence
More about me
Florian Hubrich
#Natural products
#Biosynthesis
#Extremophiles
Project Idea
Natural products are beneficial chemical molecules for their producers, e.g., for defense. Due to their very specific lifestyle, bacteria colonizing extreme habitats were longtime expected to be unable to produce natural products. However, there are a few natural products isolated from such environments but the biosynthesis remains enigmatic. With my project I aim to decipher the natural product biosynthesis of extremophiles to understand how they produce their unique chemical scaffolds and harness their potential as drug leads to tackle emerging challenges such as antimicrobial resistance.
How does the KT Boost Fund support you and your project idea?
The Klaus Tschira Boost Fund offers me the opportunity to pursue a research project that is clearly distinguished from everything I did in the past which will underline my independence and creativity as a natural product researcher. The financial support will enable me to work with equipment that would otherwise be inaccessible in my position as a junior research group leader. The proposed project represents not only a corner stone for my personal scientific career, it has the potential to contribute to a broader understanding about specialized metabolism evolution.
If I had more time for things other than research, I …
…would spend more time with my family and friends. In addition, I would spend more time for training to qualify again for the Ironman Hawaii.
Profile
Name: Florian Hubrich
Research field:Natural product biosynthesis
Institution:Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS) and Saarland University, Department of Pharmacy
More about me
#Plant Genomics
#Crop Diversity
#Domestication
Project Idea
Developing next-generation crops that address climate change, food security and nutrition requires expanding our understanding of underutilized species. Mashua, a high-yielding Andean tuber more nutritious than potato, serves as a test case for unlocking the potential of such crops. However, its adoption is limited by undesirable flavors and its cultivation restricted to certain latitudes. Using multi-omics, we will study the biological basis of these traits to enable targeted domestication. This project demonstrates how modern breeding can transform underexplored crops into resilient options.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund provides a unique opportunity to advance my research and grow as a scientist. It will allow me to develop expertise in genome sequencing and bioinformatics while fostering collaborations with experts in metabolomics and crop science. Additionally, the funding will give me valuable leadership experience by coordinating a small team, helping me build the skills needed to drive independent research projects in the future.
If I had more time for things other than research, I …
…would spend more time with family and friends, do more sports, and enjoy fishing, hiking, bouldering, cooking, and snowboarding.
Profile
Name: Dr. Pascal Hunziker
Research field: Plant Biology
Institution: Heidelberg University, Centre for Organismal Studies (COS)
More about me
Institutional website
ResearchGate
ORCiD
Google Scholar
Bluesky
#Paleoclimate
#Speleothems
#(Isotope) geochemistry
Project Idea
If we want to better understand anthropogenic climate change, more precise information on past climate dynamics is needed. The chemical and isotopic composition of cave speleothems (e.g., stalagmites) provides such information, reflecting fluctuations in climate conditions over the period in which they were formed. In this project, unique speleothems from South Patagonia will be analyzed to obtain data for the reconstruction of paleoclimate variability at high resolution. This will contribute to a deeper understanding of the evolution of the Southern Hemispheric climate during the Holocene.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund scheme ideally contributes to my professional and personal development. It serves as the cornerstone for my research focusing on the impact of changing climate conditions and other environmental controlling factors on the evolution of pristine ecosystems. I consider this financial support as an important step to achieve scientific independence. It will enable me to better establish in speleothem research, will allow me to acquire funding for a senior academic role, and to conceptualize proposals for extensive follow-up projects.
If I had more time for things other than research, I …
… would definitely spend more time with my family and friends, including joint travel to high-latitude regions and various outdoor activities (e.g., biking, fishing, and photography).
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Name: Dr. Björn Klaes
Research field: Earth surface biogeochemistry; paleoclimate and paleoenvironmental reconstruction
Institution: Trier University, Faculty VI: Spatial and Environmental Sciences, Geology Department
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Anthodesmi Krontira
#Neurodevelopment
#Cortical neurogenesis
#Brain repair
Project Idea
In most mammals, neurogenesis, the process of generating neurons from progenitor cells, ends around birth. The cerebral cortex, which wraps the brain’s hemispheres and is essential for cognitive functions, lacks adult neurogenesis. Consequently, cortical neurons lost during injury or disease aren’t naturally replaced. My project will investigate whether we can maintain progenitor cells that retain the ability to produce cortical neurons after birth. The goal is to extend cortical neurogenesis into postnatal life and potentially adulthood, enabling cortical neuron regeneration when needed.
How does the KT Boost Fund support you and your project idea?
The support from the Klaus Tschira Boost Fund at this critical career stage of my career provides me with the resources, time, and training necessary to prepare me for the transition to independent positions. KT funding enables me to pursue a technically challenging cortical neurogenesis project with access to dedicated technical help. With reduced technical demands, I can focus on advanced responsibilities like student mentorship and strategic project planning. The fund will also support conference attendance and open access publishing, fostering international collaborations both now and in the future.
If I had more time for things other than research, I …
…would volunteer at a dog shelter and walk dogs regularly; I would travel as much as possible with my family and friends and I would spend more time near the sea.
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Name: Anthodesmi (Anthi) Krontira
Research field: Neurodevelopment and Neurobiology
Institution: Helmholtz Center Munich, Institute of Stem Cell Research and Ludwig-Maximilians-Universität München, Division of Physiological Genomics
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#Kinomics
#Atherosclerosis
#Kinase
Project Idea
Heart attacks and strokes, driven by clogged arteries caused by atherosclerotic plaque rupture, remains the leading cause of death globally. Existing treatments only lower the risk by 30-40%, highlighting the urgent need for new therapies.
Kinases, proteins that regulate vital cellular processes, play a key role in disease progression. Using a kinomics platform, I aim to identify specific kinases involved in plaque rupture and assess their potential as biomarkers to predict heart attacks or strokes. This research could lead to innovative treatments and a non-invasive test for earlier risk detection.
How does the KT Boost Fund support you and your project idea?
The Klaus Tschira Boost Fund helps me develop independent research ideas and explore new approaches that would otherwise remain untapped. It allows me to connect with researchers from different fields, encouraging collaborations and fresh perspectives to improve my work. The funding also supports my leadership growth by enabling me to mentor a PhD student. With this extra support in the lab, we can accelerate experiments and gather vital data to address heart disease, one of the leading global causes of death. Without this funding, these opportunities would remain unrealized.
If I had more time for things other than research, I …
…would love to dedicate more time to dancing salsa. It combines my love for sport, music, and culture. Attending international salsa festivals is the perfect blend of all these interests.
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Name: Sanne Maas
Research field: Cardiovascular research
Institution: RWTH Aachen University, Aachen-Maastricht Institute for CardioRenal Disease
#Nucleolus
#Ribosomal proteins
#Biomolecular condensates
Project Idea
The molecular machine that produces all proteins in every living being is itself made of proteins and RNA. In eukaryotes, this machine, called the ribosome, is assembled in a specialized compartment of the nucleus called the nucleolus. In this ‘ribosome factory’, 80 ribosomal proteins must meet four RNAs to build a functional ribosome. Although essential for life, this process is not fully understood. With the KT Boost Fund, I will systematically identify the ‘address tags’—peptide sequences that guide ribosomal proteins to the nucleolus—using a newly developed high-throughput imaging approach.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund came at the perfect time for me, giving me the opportunity to establish my independent line of research and hopefully make the leap to full independence. I’m incredibly excited to work on a project that will provide unprecedented data to the intrinsically disordered protein and biomolecular condensate communities. Since time is of the essence—both for my career development and the project’s timeliness—this funding enables essential experiments, expands my network, and accelerates my transition to scientific independence.
If I had more time for things other than research, I …
…would train to beat my 10K record, finally master the cello and start a trio at home, spend weekends rowing and sailing, and use my spare time to help make Berlin cleaner by collecting waste.
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Name: Katrina Meyer
Research field: Molecular Biology
Institution: Max-Planck-Institute for Molecular Genetics
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Mirja Mittermaier
#Artificial Intelligence
#Chronic Lung Diseases
#Digital Biomarker
Project Idea
As a computer scientist and specialist in internal medicine with a focus on respiratory medicine, the aim of my research is to improve the diagnosis and treatment of lung diseases with the help of artificial intelligence. For example, I am developing digital biomarkers that are suitable for monitoring the progression of chronic lung diseases.
How does the KT Boost Fund support you and your project idea?
I am convinced we are only beginning a new era of how (digital) computer sciences, combined with “classic research,” are conducted. I aim to contribute to building and shaping the rapidly evolving field of applied computer science in respiratory medicine. I am convinced that this fellowship will be an important catalyst for my development and will be suited to build upon my training as a clinician, researcher, and computer scientist. The Boost would allow me to start a research project at the intersection of computer sciences and respiratory medicine.
Further, I consider the Boost fund a great opportunity to expand my leadership and communications skills, which are extremely important when working in new and intersectional fields. And I am looking forward to learning from my co-fellows about their ideas, problem-solving strategies, leadership style, and, of course, their projects.
If I had more time for things other than research, I …
…would give more lectures on the benefits of artificial intelligence in health care; I would invest more time in mentoring young female scientists; and I would actively work to teach children programming at an early age.
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Name: Dr. med. Mirja Mittermaier
Research field: Artificial Intelligence and Digital Health in Respiratory Medicine
Institution: Charité – Universitätsmedizin Berlin, Department of Respiratory Medicine and Critical Care Medicine with Sleep Medicine
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Mariia Nesterkina
#Infections
#Skin
#Drug Delivery
Project Idea
Many skin infections are challenging to treat because conventional drugs can not penetrate deeply enough or release their effects at the optimal time. This project investigates thermotropic liquid crystals (LCs) – materials that transition from a crystalline to an LC phase, enabling controlled drug release. Derived from natural products, these LCs enhance drug delivery efficiency and enable the development of “smart” wound dressings that respond to changes in the skin, offering improved treatment for infections such as cutaneous leishmaniasis and tuberculosis.
How does the KT Boost Fund support you and your project idea?
The Klaus Tschira Boost Fund is pivotal in advancing my career toward becoming an independent researcher and future group leader. It will enable me to establish my research group “Smart Pharmaceutical Materials and Systems” and pursue leadership opportunities at Helmholtz Institute. This funding supports key collaborations, essential resources, and conference participation, accelerating my transition to a professorship. Without it, my potential for growth and leadership within the research community would be significantly constrained, delaying progress toward my career goals.
If I had more time for things other than research, I …
…would begin my political career to influence research funding, advocating for its increase. A key dream is to establish my own Foundation to support researchers-at-risk, enabling their scientific progress
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Name: Dr. Mariia Nesterkina
Research field: Pharmaceutical Technology
Institution: Helmholtz Institute for Pharmaceutical Research Saarland
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Jan Pennekamp
#Synthetic data generation
#Data fidelity checks
#Research best practices
Project Idea
Utilizing personal healthcare data promises significant benefits for individuals and the society alike, but such a practice also comes with diverse (privacy) risks. As a result, research suggested to substitute or complement real patient data with synthetic data. However, so far, the implications of these actions are underexplored. This project intends to close this research gap by studying whether real patient data and synthetic data yield identical (or at least comparable) research findings. This way, we want to bring clarity and provide a good basis for future research activities in healthcare.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund is a great opportunity for pursuing interdisciplinary research since attracting funds for interdisciplinary topics is often a challenge. With this support, I can enjoy working independently (!) with talented researchers, who are at different stages of their careers, each bringing a unique background to the table. Career-wise, the project allows me to establish a solid foundation for larger follow-up funding while alleviating some of academia’s pressure; with the aim of sustaining a long-term academic career. Fingers crossed! Looking forward to a continued interdisciplinary exchange.
If I had more time for things other than research, I …
…would substitute some of the research to source the “freed” energy to (again) purse a more active lifestyle: (mountain) hiking, gym workouts, cooking and baking, attending concerts, and being active in general.
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Name: Jan Pennekamp
Research field: Interdisciplinary Application of Security and Privacy (Computer Science background)
Institution: RWTH Aachen University, Communication and Distributed Systems
More about me
#Mosquitoes
#Climate change
#Ecology
Project Idea
Climate change shifts the risk of mosquito-borne disease outbreaks to new regions. In urban areas, container-breeding mosquitoes like Aedes albopictus or Culex pipiens are the dominant species and important vectors of pathogens such as dengue and West Nile virus. My project aims to develop a cost-effective experimental field set-up to analyse climate change effects on the mosquito population dynamics. The findings can improve risk predictions and support strategies to mitigate mosquito-related health threats in a warming world.
How does the KT Boost Fund support you and your project idea?
The Klaus Tschira Boost Fund allows me, for the first time, to take full responsibility for my own research project. This marks a crucial step toward scientific independence and provides valuable experience in project management. Within the project, I aim to establish a novel field approach to study the effects of climate change on mosquitoes. Its successful implementation would create opportunities for follow-up research in the interdisciplinary field of vector ecology.
If I had more time for things other than research, I …
…would spent more time in the nature and with friends. I would also like to read more, play more tennis, and probably start with voluntary work in a sports club.
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Name: Felix Sauer
Research field: Ecology
Institution: Bernhard Nocht Institute for Tropical Medicine, Department of Arbovirology and Entomology
More about me
Institutional website
ResearchGate
Photo credit: © BNITM / Dino Schachten
#Geology
#Neural Networks
#Resource Management
Project Idea
Three-dimensional geological models predict the distribution of rock types underground. These predictions are needed to manage resources like water, minerals and energy, and to understand earthquakes, landslides and other geohazards. But, geological models are always uncertain: drilling to extract samples is very expensive, and geologists typically disagree on how to interpret them. In this project I help to reduce this uncertainty, using neural networks that integrate diverse data to help us better constrain the geological structures that shape the Earth and our interactions with it.
How does the KT Boost Fund support you and your project idea?
The Boost Fund is helping me realise the potential of my ideas, by (1) providing a platform through which I can demonstrate their significance, and (2) giving me the opportunity to begin building a research group and so explore them in depth. It also fills an important funding niche, allowing me to initiate fundamental yet inherently cross-disciplinary research that would otherwise be challenging to attract funding for.
If I had more time for things other than research, I …
…would sail the world. Sailing provides a fantastic way to experience our dynamic and rapidly changing planet, and to explore new places and cultures.
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Name: Sam Thiele
Research field: Geology, Data Science
Institution: Helmholtz Center Dresden Rossendorf, Helmholtz Institute Freiberg for Resource Technology, Exploration
More about me
Personal website
Institutional website
Research group website
ResearchGate
#Genetics
#ncRNA
#Gene Regulation
Project Idea
As individuals, we are all products of our genomes. Variations in our genomes make us unique, sometimes by being transcribed into variant RNA molecules, which can be further translated into variant proteins. However, not every RNA is translated. Some RNAs remain in the nucleus, where they interact with DNA and contribute to gene regulation. This project will explore how nucleotide variants in non-coding RNAs could contribute to disease via the disruption of sequence-specific RNA-DNA interactions, further enhancing our understanding of how our genomes impact our lives.
How does the KT Boost Fund support you and your project idea?
The support of the KT Boost Fund will be multifaceted. Not only will it enable me to conduct high risk-high gain research in a burgeoning field, but it will also facilitate the establishment of collaborative relationships with world-renowned experts in gene-editing technologies. Additionally, the grant will allow me to pay forward the faith demonstrated in me by creating a PhD position, effectively representing the start of my own small, independent research group. Aside from the clear benefits to my research, I am excited by the mentoring and learning experiences that the KT Boost offers.
If I had more time for things other than research, I …
…would be outside! I love immersing myself in nature, preferably through long-distance, multi-day hikes. I find the simplicity of walking is a great antidote to the complications of everyday life.
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Name: Timothy Warwick
Research field: Biology
Institution: Goethe University Frankfurt, Institute for Cardiovascular Physiology
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Lorenz Adlung
Domenico Azarnia Tehran
Stefanie Bärthel
Sabrina B. Bennstein
Youssef El Mouali
Bennet Fischer
Clarissa Glaser
Christin Katharina Kreutz
Deniz Kumral
Eunbi Kwon
Alice Mockford
Vahid Nasirimarekani
Henri Niskanen
Frederic Alexander Römschied
Maria-Elena Vorrath
Jingyuan Xu
#Adipose tissue
#Immunology
#Computational modelling
Project Idea
Did you know that your body fat contains immune cells? Correct, our immune system is present in fat tissue! To better understand the role of immune cells in fat tissue, I will computationally analyze how different ratios between immune cells and fat cells contribute to the metabolic fitness of mice and humans. Machine learning will help me to identify factors of obese yet healthy fat tissue, which I will test in the lab when I put together different numbers of fat cells and immune cells. Thereby, I want to discover a way how our immune system can protect from type-2 diabetes.
How does the KT Boost Fund support you and your project idea?
The contribution of the Klaus Tschira Boost Fund is two-fold: 1) The highly attractive coaching package will allow me to further develop my personal skills in leadership, management, and mentoring. 2) The generous financial support will enable me to pursue a truly interdisciplinary project at the intersection of immunometabolic research and data science. I envision that the Klaus Tschira Boost fund will advance my career towards becoming an excellent and independent researcher, embedded in an international and interdisciplinary network.
If I had more time for things other than research I …
would take endless strolls with my wife and our three dogs through nature, equipped with our cameras and good books (humans) as well as a ball to play (dogs, and humans…)
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Name: Dr. Lorenz Adlung
Research field: Systems Biology
Institution: University Medical Center Hamburg-Eppendorf (UKE), Dept. of Medicine, Hamburg Center for Translational Immunology (HCTI) and Center for Biomedical AI (bAIome)
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Domenico Azarnia Tehran
#Aging
#Cellular neuroscience
#Proteomics
Project Idea
Over the course of a lifetime, age becomes the primary risk factor for cognitive decline and our increased susceptibility to dementia and neurodegenerative diseases, such as Alzheimer’s disease. Despite this, our understanding of the biology of human brain aging is still limited. In this project, our aim is to reveal the age-related changes occurring in the most abundant cells of our brain: neurons and astrocytes. Our goal is to discover the key factors that influence brain aging, which could help us identify biomarkers and develop treatments to maintain brain health as we grow older.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund provides me the essential financial and professional support to explore a creative and challenging approach focused on identifying the main pillars driving human brain aging. This represents a thrilling opportunity for my scientific career, as it will allow me to embark on a multidisciplinary project and establish my own line of research. Securing this grant will enable me to expand my collaborations and portfolio, strengthening my profile as an independent scientist. I am looking forward to being part of the KT Fellow’s network to gain fresh perspectives and share my experiences.
If I had more time for things other than research I …
would travel more with my wife and friends, spend more time with my family and nephews in Italy, and finally pursue my long-standing dream of opening my own restaurant.
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Name: Dr. Domenico Azarnia Theran
Research field: Neurobiology
Institution: Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) Berlin, Molekulare Physiologie und Zellbiologie
More about me
ORCID: 0000-0001-8955-7240
Stefanie Bärthel
#Cancer-associated fibroblasts
#Therapeutic vulnerabilites
#Pancreatic cancer
Project Idea
Pancreatic cancer is an aggressive disease with limited treatment options that is characterized by highly abundant cancer-associated fibroblasts (CAFs) mediating therapy resistance and shaping an immunosuppressive microenvironment. The aim of this project is to target and reprogram CAFs towards immune activation for improved treatment options for cancer patients. Cutting-edge technologies, such as cell-selective proteomics and Spatial Transcriptomics, will be used to uncover functional states of distinct CAF subpopulations under basal conditions and in response to a novel combinatorial therapy.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund supports my project with the overarching aim to improve therapeutic treatment options for pancreatic cancer patients. The funding provides me with the necessary resources to develop independent research ideas, collaborate and network with interdisciplinary experts, facilitate my scientific contribution and impact, as well as develop essential leadership skills. Overall, the KT Boost Fund will play a critical role in enabling me to achieve my short- and long-term career goals and make significant contributions to the field of cancer research.
If I had more time for things other than research I …
would pursue many of my interests more regularly, including gardening, voluntary work abroad, traveling the world with friends, long-distance hiking, and spending more quality time with family and friends.
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Name: Dr. Stefanie Bärthel
Research field:Translational Cancer Research and Experimental Cancer Therapy
Institutions: German Cancer Research Center (DKFZ) Heidelberg and Munich / Translational Cancer Research and Experimental Cancer Therapy
More about me
#Developmental immunology
#Immunodeficiency
#scRNAseq
Project Idea
This project focuses on the developmental needs of rare inborn immune cells, called innate lymphoid cells (ILCs). Our data suggests a developmental origin of human ILCs within the thymic gland. To test this hypothesis, we will analyze the blood of patients with inborn genetic defects causing underdeveloped thymic tissue and study the appearance, frequencies, and messenger RNAs of ILCs as well as all lymphocytes on a single cell level. These patients represent a unique opportunity to study thymic involvement in human ILC development.
How does the KT Boost Fund support you and your project idea?
I will gain the opportunity to analyze ILC phenotypes in immunodeficient patients, representing a unique possibility to observe ILCs in an ex vivo context of a well-defined immunodeficiency without using a model organism. Getting funding for this project is a unique opportunity to pave my future career path into using clinical samples to understand human ILC biology and developmental needs, to deepen my skills in analyzing scRNA-seq data sets, and strengthen my independence as a postdoctoral researcher.
If I had more time for things other than research I …
would like to spend more time with my family, and friends, and have more time on my own, where I can do more sports, read a book, or just enjoy the view to better recharge my energy deposits.
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Name: Dr. Sabrina B. Bennstein
Research field: Immunology
Institution: Heinrich-Heine-University Düsseldorf, Medical Faculty, Institute for Transplantation Diagnostics and Cell Therapeutics, AG Uhrberg
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#Microbiome
#RNA-mediated regulation
#Human gut colonization
Project Idea
Microbial communities are present on every surface of our planet, which includes our skin, cavities, and intestinal tract. The human gut microbiota plays a prominent role in human health and alterations in its microbial composition have been associated with a plethora of human diseases. A current limitation in the field is the inability to explore functionally these associations as we know very little about most of these microorganisms. This project aims to uncap some of these limitations by developing genetic tools to dissect how these microorganisms colonize the human gut.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund will allow me to broaden the scope of my current project and enable me to attempt higher risk-reward approaches to dissect genetic networks important for commensal bacterial colonization of the human gut. At the end of the proposed research plan, I aim to establish myself as an independent researcher focused on depicting how mechanistically bacteria colonize our gut, for this, the KT Boost Fund expertise on career guidance as well as the network opportunities will play a major role within the next 2 years where I will be working towards establishing my independent research group.
If I had more time for things other than research I …
would go back home more often (and for longer) to visit my family and friends.
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Name: Dr. Youssef El Mouali
Research field: Microbiome / RNA Biology / Molecular Microbiology
Institution: Helmholtz Centre for Infection Research (HZI), Dept. of Microbial Immune Regulation
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#Optical 3D Printing
#Meta-fibers
#Inverse Design
Project Idea
Optical image processing is typically performed digitally; thus, always requiring energy for operation. A more efficient way of processing such signals is directly by using the required imaging optics. My research focuses on fiber-based meta structures, i.e., structures with a feature size smaller than the used light, which passively allows imaging and processing simultaneously. Implementing such complex structures requires advanced design and fabrication techniques. To overcome this, I investigate computer-aided inverse design and optical 3D printing for novel optical processing meta-fibers.
How does the KT Boost Fund support you and your project idea?
The Boost Fund allows me to explore my own research ideas in a highly interesting and competitive field, enabling me to build a first cornerstone as an independent researcher. The flexible funding allows hiring and training of the next generation of scientists and engineers in a fast-moving research field, as well as purchasing unique equipment for the realization of my project. Importantly, the training and networking aspect of the KT funding is unique, encouraging and enabling networking and collaborative research beyond traditional funding programs.
If I had more time for things other than research I …
would spend more time traveling, and exploring the world, different cultures, and delicious food. I would also spend more time in nature, going hiking and biking over the alps.
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Name: Dr. Bennet Fischer
Research field: Photonics
Institution: Leibniz Institute of Photonic Technology Jena
#Hydrology
#Headwater streams
#Groundwater – surface water exchange
Project Idea
Headwater streams serve as the origins of all river networks, constituting nearly 90% of the global river network length. These streams are currently undergoing, and will continue to undergo, a reduction in stream flow due to the impacts of climate change. A distinctive feature of headwater streams is their pronounced interaction between groundwater and stream water. Our comprehension of how this exchange will evolve under diminished stream flow is still limited. In my research, I aim to close this research gap and predict exchange processes with field-based data and hydrological modeling.
How does the KT Boost Fund support you and your project idea?
The Boost Fund offers a remarkable opportunity to address crucial research questions concerning hydrological processes in headwater streams. It empowers me to establish myself as a strong young key scientist in the field, while simultaneously pushing the boundaries of hydrological knowledge. Furthermore, this funding facilitates a research stay at Oregon State University (USA), fostering collaborations with international researchers and amplifying the growth of my scientific network.
If I had more time for things other than research I …
would explore nature on hikes and trail runs all across the world, most likely always close to beautiful streams. Furthermore, I would enjoy more board game nights with my friends.
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Name: Dr. Clarissa Glaser
Research field: Hydrology
Institution: University of Bonn, Dept. of Geography
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Christin Katharina Kreutz
#Large language models
#Argument recommendation
#User studies
Project Idea
Large language models (LLMs) such as ChatGPT are becoming very popular and are used in a wide range of areas to automatically generate text. At the same time, concerns arise about them possibly producing harmful texts containing hallucinations. Recommending arguments to persons who want to inform themselves about pro and contra viewpoints on topics is an especially vulnerable area for using LLMs. In this project, we investigate risks associated with using LLMs to personalize convincing arguments and how LLMs can be used to suggest the most suitable arguments to individuals.
How does the KT Boost Fund support you and your project idea?
The Boost Fund enables me to broaden my research portfolio through an interdisciplinary project enriching computer science methods with a psychological viewpoint on opinion formation. Without the fund, it would be impossible to take on this time-sensitive research project on LLMs and conduct resource-intense user studies to capture human perspectives. Additionally, our project allows me to expand my research network and establish national and international cooperations with a four-month research visit to Australia.
If I had more time for things other than research I …
would bake a cake every week for my office mates to enjoy, grow more veggies in our greenhouse and go on more short trips with my family and friends.
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Name: Dr. Christin Katharina Kreutz
Research field: Computer Science
Institution: TH Köln – University of Applied Sciences, Faculty of Information Science and Communication Studies, Institute of Information Science
More about me
#Slow wave sleep
#Metabolic waste products
#Brain imaging
Project Idea
Sleep is essential for brain health. During sleep, our brain goes through different stages, including slow-wave sleep (SWS), which plays a restorative role. SWS helps clear metabolic waste products like amyloid-ß, a substance linked to Alzheimer’s Disease (AD). However, the direct effects of SWS disruption are unknown. In this research, we will use advanced brain imaging and computational methods to study the impact of SWS on clearing waste products and how it affects memory consolidation during sleep. This will give us valuable insights into age-related neurodegenerative diseases like AD.
How does the KT Boost Fund support you and your project idea?
The Boost Fund will be instrumental in covering the essential experimental costs, and materials, and providing research assistants, all of which are crucial for the success of my research proposal. Beyond financial support, the Klaus Tschira Alumni Network offers invaluable opportunities for mentoring and networking, enabling collaborations with national and international experts in the field. This support is necessary for nurturing my development as an independent researcher and fostering an environment where innovative research can thrive.
If I had more time for things other than research I …
would explore museums, cultural events, and film festivals. All above spending quality time with my family and visiting my parents in Turkey would be my top priorities.
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Name: Dr. Deniz Kumral
Research field: Cognitive Neuroscience
Institution: Albert-Ludwigs-Universität Freiburg, Neuropsychology, Psychology
More about me
Eunbi Kwon
#Bird migration
#In-flight vocalization
#Conspecific attraction
Project Idea
All animals choose where to breed, and this decision shapes the population as well as the species distribution. Understanding the drivers of habitat selection is the fundamental quest in ecology. Conspecific presence can attract settlement, but it has been virtually impossible to monitor the dynamic social environment while animals prospect for future breeding habitats. We aim to develop a miniature GPS audio transmitter that can simultaneously record sound as a bird migrate, and test if conspecific social interactions increase the likelihood of prospecting birds to settle at the location.
How does the KT Boost Fund support you and your project idea?
The Boost Fund will support my collaboration with the leading developer of animal tracking devices to develop a new ‘GPS-audio-transmitter’ that combines cutting-edge GPS transmission technology with a biotelemetry of vocalization. The funding will also support a field project to test the device on migrating shorebirds in the wild and a training opportunity for students to interpret sound recordings into social interactions. This new biotelemetry device will be highly versatile to address questions in many other fields of study and thereby will expand my area of research.
If I had more time for things other than research I …
would love to travel for a year following shorebirds as they migrate and explore new and familiar sites. Spotting new species of shorebirds along the way that I have not seen before will be a bonus.
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Name: Dr. Eunbi Kwon
Research field: Field Ornithology / Behavioral Ecology
Institution: Max Planck Institute for Biological Intelligence, Dept. of Ornithology
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Alice Mockford
#Ecosystem services
#Global change
#Landscape ecology
Project Idea
Insects support functioning ecosystems and provide services for human health and well-being. However, with climate change and biodiversity loss, these vital services are under threat. Greenveins, such as hedgerows and forests, regulate microclimate and support biodiversity and ecosystem services, so their management could help support beneficial insects under global change. This project aims to find out whether the complexity of green veins across landscapes and climate zones could help minimize the adverse effects of extreme high-temperature events and support ecosystem services.
How does the KT Boost Fund support you and your project idea?
The Boost Fund will make a profound contribution by driving three interdependent phases of my early career, to 1) conduct novel and collaborative research on the combined risk of biodiversity loss and climate change; 2) build the foundations that will strengthen my research profile and facilitate research autonomy; and 3) develop my skill set through mentorship and workshops. The fund will also allow me to attend key conferences and publish open access. This will enhance the dissemination of the results, which I hope will lead to the development of more sustainable policies under global change.
If I had more time for things other than research I …
would like to go on more adventures: hiking, traveling, and exploring. I’d also like to dedicate more time to art; I always loved drawing and painting but I rarely find time to practice.
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Name: Dr. Alice Mockford
Research field: Ecological Entomology
Institution: Christian Albrecht’s University of Kiel, Institute for Natural Resource Conservation, Dept. of Landscape Ecology
Vahid Nasirimarekani
#Origin of life
#Liquid-liquid phase separation
#Biomolecules self-assembly
Project Idea
How life has formed and evolved on our planet is a little-known field of study. Going back in time, we know that the early seawater had the basic ingredients to form a minimal cell that could potentially reproduce. However, we do not know where exactly this process took place. I propose that small droplets of seawater landed on certain surfaces, and the water went under evaporation and hydration cycles. This process along with external factors like light, heat, and magnetic field might result in a life-like interaction between the basic biomolecules.
How does the KT Boost Fund support you and your project idea?
Any risky and innovative idea requires a certain level of theoretical or experimental evidence to be accepted. In addition, being independent and working on one’s own project in a scientific environment requires financial support. The realization of these two aspects is very important at this stage of my career. My proposal targets an unknown and risky scientific topic that needs to be experimentally validated to convince the relevant scientific community, and the contribution of the Boost Fund would therefore be very important and essential.
If I had more time for things other than research I …
Spend days in the wild nature and take pictures of small details. Walk across the countries and continents and write down the deep conversations with many people on the way. Speak many languages fluently.
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Name: Dr. Vahid Nasirimarekani
Research field: Origin of life / active biological matter, self-assembly, and self-organization
Institution: Max Planck Institute for Dynamics and Self-Organization, Laboratory for Fluid Physics, Pattern Formation and Biocomplexity (LFPB)
More about me
Instagram @nasirivahid
Henri Niskanen
#Biomolecular condensates
#Transcriptional condensates
#Phase separation
Project Idea
Biomolecular condensates underlie many cellular processes and form aberrantly in disease. The condensate function can depend on its biophysical properties, i.e. liquid, gel-like, or solid material state. However, tools to specifically probe condensate properties are lacking. My recent work revealed a disease-associated peptide that solidifies cellular condensates. This project aims to 1) elucidate the mechanism of how this newly discovered peptide alters condensate properties; 2) develop it into a universally applicable tool to modulate condensate properties to gain insight into their functions.
How does the KT Boost Fund support you and your project idea?
This funding will help in covering the expenses for interdisciplinary work that combines biochemistry, high-resolution microscopy, and the latest genomics tools. If successful, this project will provide important proof-of-concept results for further development of specific condensate modulating tools and therapeutics. With KT Boost Fund I will gain important project management experience: how to lead a team and how to manage scientific and financial aspects of a project. I also look forward to networking and educational opportunities that are undoubtedly helpful for my next career stages.
If I had more time for things other than research I …
would spend time and travel with my family & friends. I’d enjoy more music, literature and games, and pick up my guitar once again with my old bandmates.
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Name: Dr. Henri Niskanen
Research field: Biochemistry & Molecular Genetics
Institution: Max Planck Institute for Molecular Genetics, Dept. of Genome Regulation
More about me
Frederic Alexander Römschied
#Drosophila
#Social flexibility
#Multi-animal optogenetics
Project Idea
How do brains drive social behavior? Answering this question requires precise measurements of social interactions, and interrogation of the neural circuits driving them. I propose to address this question for the social behavior of the vinegar fly Drosophila, using a novel approach that allows me to independently manipulate the social behavior of one animal and the neural circuits for control and perception of social interactions in another animal. This will open the door to an in-depth understanding of the neural mechanisms driving social behavior.
How does the KT Boost Fund support you and your project idea?
As a Postdoc, I developed an assay for social flexibility in which I perturbed social interactions between two flies, using optogenetics on one fly (A), and monitored whether this perturbation changed the behavioral strategies of the other fly (B). Boost Funding upgrades this approach, enabling simultaneous and independent manipulation (via optogenetics) of neural circuits in fly B, to uncover which neurons drive social flexibility. Thus, Boost Funding allows me to pursue an ambitious pilot project to establish my future research niche, and it provides important planning security for my family.
If I had more time for things other than research I …
dream of a more inclusive and family-friendly academia, and of stronger institutional support for first-generation academics. Outside the lab, I spend time with my family-of-5, cook, bake, and DJ.
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Name: Dr. Frederic Alexander Römschied
Research field: Computational Neuroethology
Institution: University Medical Center Göttingen, European Neuroscience Institute Göttingen
#Carbon dioxide removal
#Circular economy
#Climate mitigation
Project Idea
ROCKCHAR is a project that combines two effective methods for removing CO2 from the atmosphere: rock powder, which draws down CO2 by weathering, and biochar, which is a stable form of organic carbon. By combining waste rock powder and biomass from the industry ROCKCHAR creates synergy effects that provide affordable and environmentally friendly CO2 removal in agricultural soils. Additionally, both methods increase soil health, fertility, and drought resilience while implementing circular waste streams and generating sustainable energy.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund allows me to explore new materials and their combinations to prove if they work as an effective, environmentally friendly, and affordable future CO2 removal technology. If successful, this research would give me outstanding expertise in that field and increase my career opportunities in academia and the industry. Without funding, I could not cover the high costs of material production, analyses, and a student assistant to conduct the required experiments. The potential of safely using waste materials to create soil amendments for agriculture would remain entirely untapped.
If I had more time for things other than research I …
would like to learn how to grow vegetables (I have a black thumb) to apply my research outside the lab. I would also like to travel to give lectures and workshops, so ROCKCHAR could be used worldwide.
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Name: Dr. Maria-Elena Vorrath
Research field: Geochemistry / Carbon Dioxide Removal
Institution: University of Hamburg, Institute for Geology, Working Group of Aquatic Geochemistry
More about me
#Elatocaloric cooling
#Shape memory alloys
#Sustainable refrigeration
Project Idea
In Germany, refrigeration accounts for 14% of electricity consumption. This proportion is expected to increase steadily in the future. Innovations in cooling technology can therefore make an important contribution to climate and environmental protection. Elastocaloric cooling, based on stress-induced thermal changes in shape memory alloys, offers a promising alternative that is efficient and environmentally friendly, using solid-sate refrigerants. This research project aims to develop and demonstrate elastocaloric cooling devices with enhanced temperature range and cooling power.
How does the KT Boost Fund support you and your project idea?
The Boost Fund empowers my scientific independence, enhances my research profile, and elevates my career prospects as a junior research group leader. With flexible funding, I’ll explore solid-state cooling innovations and access vital resources to accelerate research progress. The fund’s mentorship will shape my career, promoting early independence, and fostering professional growth.
If I had more time for things other than research I …
would embark on long caravanning trips and indulge in the art of creating poetry. As a mother of a little boy, I would share these precious moments with those I love, while fulfilling my personal passions.
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Name: Dr. Jingyuan Xu
Research field: Sustainable Energy Technology
Institution: Karlsruhe Institute of Technolog, Institute of Microstructure Technology
Casey Paquola
Hilary Noad
Inmaculada Martínez-Reyes
Oya Cingöz
Renate Sachse
Sam Sanders
Susanne Wintzheimer
Svetlana Klementyeva
Zahra Razaghi-Moghadam
Ignacio Rodríguez Polo
#neuroscience #childhood development #complex biological systems
Project Idea
As a baby grows from a fetus to a child, its brain grows from a few thousand cells to over 100 billion. Understanding how cells organise themselves during this period can help us to understand the development of complex behaviours, the origins of psychiatric disorders and what makes humans unique. In this project, we will use tissue samples and magnetic resonance imaging (MRI) to investigate human brain development. We aim to model complex patterns of cellular reorganisation and thereby derive the rules that govern healthy brain development.
How does the KT Boost Fund support you and your project idea?
The Boost Fund provides an incredible opportunity to analyse a historical set of human brain tissue (collected between 1960 and 1985) that covers prenatal and childhood development. Such collections, housed in museums and universities around the world, can provide vital insight into development and evolution, but they are underutilised due to methodological difficulties (e.g. inconsistent tissue quality). We believe we can reinvigorate their use via advanced image processing and combined MRI analysis, and in doing so improve our understanding of brain organisation.
If I had more time for things other than research I …
… would read more philosophical works, especially on the nature of being, and I would spend more time immersed in nature, perhaps in German forests or on my native Australian coastline.
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Name: Casey Paquola, Ph.D.
Research field: Neuroscience
Institution: Forschungszentrum Jülich, Institute of Neuroscience and Medicine (INM-1)
Web: Multiscale Neuroanatomy Lab
Hilary Noad
#physics #pressure #electrons
Project Idea
I study the properties of crystals at very cold temperatures – at just a few degrees above absolute zero—where quantum aspects of the electrons play an important role. I learn about the electrons by applying pressure to the crystal. This can change the behaviour of the electrons just as lowering temperature changes water into ice. To do these experiments, I use equipment that doesn’t have much room inside. My project is to develop a new pressure device that is even smaller than existing ones so that I can do experiments in a new and exciting set of experimental conditions.
How does the KT Boost Fund support you and your project idea?
The KT Boost fund is helping me to bridge a technological gap between having a prototype device and having a proven, reliable device that can be used in extreme conditions. By enabling me to purchase equipment for dedicated use on my project, the KT Boost fund is accelerating the development of my device, granting me independence, and giving me crucial experience in directly managing both scientific and financial aspects of a research project.
If I had more time for things other than research I …
… would spend more time with family and friends who are scattered around the world. I would also get back into making music with other people, singing in a choir or playing my harp in an orchestra.
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Name: Hilary Noad, Ph.D.
Research field: Experimental Condensed Matter Physics
Institution: Max Planck Institute for Chemical Physics of Solids/ Physics of Quantum Materials
Website: Physics of Quantum Materials
Inmaculada Martínez-Reyes
#tumor immunology #metabolism #CRISPR screens
Project Idea
The recent successes of immunotherapies have revolutionized cancer treatment. However, treatment failure and resistance are frequently observed. Different metabolism-related factors including the competition for nutrients between cancer and immune cells affect how the immune system attacks tumors. This project aims to understand whether and how cancer cells modify their metabolism as a strategy to evade the immune system. Likewise, this project will investigate whether specific metabolic pathways hamper the ability of immune cells to eradicate tumors.
How does the KT Boost Fund support you and your project idea?
My goal is to set up an independent and fruitful laboratory to study metabolic networks in tumor immunity with the ultimate purpose of improving the efficacy of current immunotherapies. The KT Boost Fund will allow me to carry on an innovative and multidisciplinary project that will make relevant contributions to the tumor immunology field. The results of this proposal will lay the foundations for the research of my future laboratory. Furthermore, funds will help me maintain and broaden my collaborations, an essential success factor at the initial stages as an independent investigator.
If I had more time for things other than research I …
… would practice outdoor sports with my children, travel more, take piano lessons, read more books, study philosophy, engage in voluntary work and organize mentoring activities for young scientists.
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Name: Inmaculada Martínez-Reyes, Ph.D.
Research field: Tumor Immunology, Cancer Metabolism, Immunometabolism
Institution:Max Delbrück Center for Molecular Medicine – Molecular Immunology and Gene Therapy
Web: MDC
LinkedIn: Profile
Twitter: @inma_mreyes
#host-pathogen interaction #virology #innate immunity
Project Idea
Viruses and their hosts are in a constant evolutionary race, each developing new ways to counteract the other. A major host defense mechanism against infections is the interferon system, discovered over half a century ago. Interferons are best known to activate the transcription of multiple cellular genes to establish a cellular antiviral state. We will investigate how exposure to interferon alters the host cell landscape at multiple layers, and how these changes come together to restrict viral infections.
How does the KT Boost Fund support you and your project idea?
Understanding how our innate immune system interacts with and prevents the replication of viruses will provide new ways to target infections. The KT boost fund will give me the freedom to ask basic research questions in a proof-of-concept study. It will allow me to demonstrate my scientific independence, bringing to life a project that I have designed, for which I acquired funding, recruited help, established collaborations and did the work.
If I had more time for things other than research I …
… would love to travel to visit all of my wonderful friends who are now spread out all over the world.
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Name: Oya Cingöz, Ph.D.
Research field: Infection and immunity
Institution: Robert Koch Institute/Dept. of Infectious Diseases
Web: RKI/ Infectious Deseases/ Unit 18
LinkedIn: Profile
Twitter: @CingozLab
ORCID: ORCID
#soft robot design #biomimetics #machine learning
Project Idea
Soft robots have the potential to provide assistance to humans in a broad range of applications. They unfold their special potential in safe interaction with humans, where conventional robots can cause a serious risk of injury. The greatest challenge in their design is currently to develop a mechanical structure that is generally able to realize the targeted maneuvers. In this research project, a bionic design process based on machine learning will be developed to determine optimal motions of soft robots and, at the same time, generate new insights in biology within a “reverse engineering” approach.
How does the KT Boost Fund support you and your project idea?
I am currently a postdoc at the TU Munich and am therefore still at the beginning of my scientific career. This stage comes with many new, exciting, challenging and also time-consuming tasks. Especially in this demanding phase, the Klaus Tschira Boost Fund offers me the opportunity to allow myself the time and the resources needed to familiarize and dig into new research fields as well as to apply them and generate own research ideas. Therefore, the funding helps me to broaden my portfolio and increase my chances for future career steps in academia.
If I had more time for things other than research I …
… would spend more time with my family in nature and pursue music and sports. In contrast to my job, I would do more hands-on work, such as crafting, or simply get carried away while reading an exciting book.
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Name: Dr.-Ing. Renate Sachse
Research field: Computational and structural mechanics
Institution: Technical University of Munich, TUM School of Engineering and Design, Institute for Computational Mechanics
Web: Institute for Computational Mechanics
#computability theory #models of computation #logic in computer science
Project idea
When you look closely at a computer screen, you observe that the picture consists of tiny pixels. This is just an example: all digital information is composed of discrete units, right down to the foundations, including Alan Turing’s famous ‘machine model’. Then, how should we compute with the non-discrete objects from e.g. mathematics and physics? Stephen Kleene has provided one answer via his computation schemes S1-S9, with some drawbacks. During my project, I will develop an alternative approach to computing with non-discrete objects, marrying the best of the Turing and Kleene approach.
How does the KT Boost Fund support you and your project idea?
The funding provided by the Klaus Tschira Boost Fund will (i) sponsor an interdisciplinary project in the intersection of computer science and mathematics, and: (ii) allow me to focus full time on the development of a new model of computation that acts directly on higher mathematics and combines the advantages of the known approaches, and: (iii) provide the necessary opportunities to promote this new model (through travel, conferences, workshop organisation) and attract researchers to my research enterprise.
If I had more time for things other than research I …
… would teach myself a number of new languages. I would like to master Japanese, Italian, and Norwegian.
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Name: Sam Sanders, Ph.D.
Research field: Computability theory/ Models of computation/ Logic in computer science
Institution: Ruhr University Bochum, Department of Philosophy II
Web: Personal Website
#supraparticles #nanoparticle assembly #catalysis
Project Idea
Praline makers combine diverse ingredients, such as chocolate, cacao powder, or sugar sprinkles, with different properties for the creation of truffle balls with an optimized taste and a certain size for better bare hand eating. Transferring this concept to materials chemistry, the combination of various materials yields a composite material with optimized performance and a certain size for better handling. Inspired by praline makers, in this project, millimeter-sized composites as support materials for catalysis are created.
How does the KT Boost Fund support you and your project idea?
The Klaus Tschira Boost Fund allows me to dive into a novel research field of millimeter-sized composites creation and the interdisciplinary assessment of their use as support materials for catalysis. This will be realized via a close collaboration of materials chemists with chemical engineers and may lay the foundations for further projects in the future.
If I had more time for things other than research I …
… would travel around the world with my husband and two children or spend more time in my garden growing flowers.
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Name: Dr. Susanne Wintzheimer
Research field: Materials Chemistry
Institution:Friedrich-Alexander-Universität Erlangen-Nürnberg / Department of Chemistry and Pharmacy / The Supraparticle Group
Web: The Supraparticle Group
#lanthanides #cluster #magnetismmemory
Project Idea
The main goal of the project is developing new classes of dinuclear lanthanide complexes with bridging inorganic cluster ligands with promising applications for design of high-performance single molecule magnets. Such molecule devices can increase the efficiency of existing processes in processing and storage of information, or advance new technologies, for example in spintronics or molecular cooling. Bridging species have a great impact on the magnetic exchange between two lanthanide centers. The project idea concerns the novel clusters to insert them between magnetic centers.
How does the KT Boost Fund support you and your project idea?
The funding from the KT Boost Fund would be an essential step for me to continue my career in science and to set up my own junior research group. Another great opportunity is to purchase a glove box, which is absolutely necessary to ensure my independent work for years or maybe decades, because the target products are extremely sensitive to air and moisture. Without funding, I would have had to put on hold my plans to create my own group. Indeed, early career support from KT Boost Fund could advance my research to a new level.
If I had more time for things other than research I …
… would do research to catch up during the pandemic. Then I would spend this time with my children without feeling guilty about being at work.
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Name: Dr. Svetlana Klementyeva
Research field: Coordination and organometallic chemistry of rare earth metals
Institution: University of Tübingen / Institute of Inorganic Chemistry
Web: Institutional (AG Schnepf)
#metabolite-protein interactions #machine-learning approaches #constraint-based metabolic models
Project Idea
The map of metabolite-protein interactions is key to specifying the mechanisms underlying the mutual feedbacks between transcription and metabolism. Integrating the map of such interactions in genome-scale metabolic networks improves predictions of growth and other metabolic traits that depend on metabolism. This project will both contribute to discovering new principles of cellular regulation with novel machine-learning approaches and to characterizing their role via in silico experiments in the constraint-based modeling framework.
How does the KT Boost Fund support you and your project idea?
With the opportunity provided by The Klaus Tschira Boost fund, I hope to further extend my experiences by supervising a PhD student and to develop my academic expertise. This would help me establish my own line of research, expand my scientific network, and promote me to the level of an independent group leader.
If I had more time for things other than research I …
… would spend more time with my loved ones, learn a language, travel more often, play board games with friends, watch more movies, …
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Name: Dr. Zahra Razaghi-Moghadam
Research field: Systems biology
Institution: University of Potsdam, Institute of Biochemistry and Biology, Bioinformatics & Max Planck Institute of Molecular Plant Physiology, Systems Biology and Mathematical Modelling
Ignacio Rodríguez Polo
#Gastruloids
#Non-human primates
#Primordial germ cells
Project Idea
My research programme focus on studying primordial germ cells (PGCs), the early embryonic precursors of sperm or eggs. For this, I will make use of gastruloids, an in vitro model of early embryo development. I aim to generate and study human and non-human primate gastruloids.
Using both species in parallel will open up the possibility to dissect potential similarities and differences between human and NHP early development. Altogether, this project will constitute a defined in vitro 3-dimensional system to study PGC specification in primates and contribute to the 3Rs in animal experimentation.
How does the KT Boost Fund support you and your project idea?
The support of the Klaus Tschira Boost Fund (KTB) will allow me to generate 3D primate gastruloids with spatio-temporal organization and PGC competence. Additionally, KTBF will potentiate the international collaboration of the two different research groups involved in this project, Dr.Ufuk Günesdogan (Georg August University of Göttingen), and Dr. Naomi Moris (Francis Crick institute of London).
Taken together, the funds and the scientific network of the KTB will significantly enhance my career prospects towards my aim of becoming an independent researcher directing my own research program.
If I had more time for things other than research I …
would spend more time with my loved ones, travel for longer periods, and develop my passions, i.e., climbing, cooking
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Name: Dr. Ignacio Rodríguez Polo
Research field: Translational stem cells research/ Developmental biology
Institution:
(1) Georg August University of Goettingen/Göttingen Center for Molecular Biosciences (GZMB)/Dept. of Developmental Biology
(2) The Francis Crick Institute, London
More about me
-Twitter: @PoloAug
-LinkedIn: Ignacio Rodriguez Polo
-ResearchGate: https://www.researchgate.net/profile/Ignacio-Rodriguez-Polo
–https://orcid.org/0000-0003-1254-4972
Anna Schulz
Christoph Heyl
Claudia Bizzarri
Daniel Carlson
Emmanuelle Quemin
Felix M. Key
Florian Loebbert
Georgios Gkatzelis
Katharina Baum
Matthew Agler
Mine Altinli
Miriam Menzel
#T-cell metabolism #Adaptive immunity #Infection control
Project Idea
T-cells are ‘the army’ of the adaptive immune system, which protects us against harmful viruses and bacteria. During infection, T-cells adapt from resting into specialized effector cells, rapidly expand in numbers and kill infected cells. But in order to switch function, T-cells need fuels like nutrients and small molecules called metabolites which they take up from their local environment. In my project, I will tackle the mystery which metabolites affect T-cell function most. And, could it be possible that bacteria in the gut impact the composition of these molecules in a nearby organ?
How does the KT Boost Fund support you and your project idea?
The funding via the KT Boost Fund will increase my level of scientific independence, strengthen my research profile and develop my career prospects towards an independent junior research group leader assignment. In the next couple of years I will work on these goals with the help of the GSO through further refining and developing my personal and professional profiles, while project funds from the Klaus Tschira Foundation will enable the implementation of my project ideas.
If I had more time for things other than research I …
… would spend more time with playing my piano, do long hiking tours and resume my sports training. With two small children and a research career, spare time is scarce and the most precious good I have to be shared with my loved ones.
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Name: Dr. Anna Schulz
Research field: Immunology, Metabolism, Viral infections
Institution: Chair of Animal Physiology and Immunology, TUM School of Life Sciences, Technical University of Munich
Web: TUM-Chair of Animal Physiology and Immunology
Christoph Heyl
#light-matter interaction #laser-physics #contact-free light control
Project Idea
This project targets a very basic question from a new perspective: How can we control the directional propagation of light? In contrast to photons, particles such as electrons or ions can be directed via free-space control mechanisms utilizing electric or magnetic fields without requiring the interaction with solid matter. A similar efficient but contact-free control option is not available for light. In this project, we plan to explore a new method employing classical light-matter interaction in gases, promising contract-free control possibilities for coherent light such as laser beams.
How does the KT Boost Fund support you and your project idea?
I am currently holding a joint appointment as a junior research group leader at the Deutsche Elektronen-Synchrotron DESY in Hamburg and at the Helmholtz-Institute Jena. With the Klaus Tschira Boost Fund, I would like to leverage scientific independence by starting a new research direction complementing my ongoing activities ranging from precision spectroscopy to lasers for modern laser-driven accelerators. In addition, the Klaus Tschira Boost funds will help consolidating recently stated cross-disciplinary collaborations e.g. with the Technical University of Darmstadt.
If I had more time for things other than research I …
… would spend more time with my family. In addition, I would embark on designing novel cargo-bikes or engage in clean energy production activities.
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Name: Dr. Christoph M. Heyl
Research field: Laser physics
Institution: Deutsches Elektronen-Synchrotron DESY & Helmholtz-Institute Jena
ResearchGate: Christoph Heyl
Web: DESY; Helmholtz Institute Jena
Claudia Bizzarri
#Photocatalysis #CO2 Capture #Utilization
Project Idea
Carbon dioxide is one of the most abundant greenhouse gases that significantly contributes to global climate change. Inspired by Nature, where photosynthesis converts light, water and CO2 into chemical energy, this project manages CO2 waste as a resource exploiting renewable energy such as visible light to access an eco-friendly lifecycle of chemical products. The utilisation of CO2 as raw material is one of the key challenges in modern chemistry, requiring highly efficient catalysts and renewable energy sources. We will develop smart photocatalytic materials and exploit them in photoelectroreduction of CO2.
How does the KT Boost Fund support you and your project idea?
The Klaus Tschira Boost Fund will aid me in exploring new pathways for the capture and utilisation of CO2, giving me the chance to start new interdisciplinary collaborations at the interface between Chemistry and Physics. I can hire a PhD student who will experience the beauty of fundamental research, also having a taste of future (industrial) applications. I will be able to buy specialised equipment and chemicals, and receive further support for publication costs and travel expenses. Last but not least, I am thrilled I can participate in the networking activities and workshops of the KT Boost Fund Program, supporting my determination to achieve my professional goals with a powerful stimulus.
If I had more time for things other than research I …
… would play longer with my daughter, visit more often my family in Italy and join a choir!
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Name: Dr. Claudia Bizzarri
Research field: Photoactive metal complexes for catalysis and bioimaging
Institution: Karlsruhe Institute of Technology, Institute of Organic Chemistry
Web: Bizzarri Group
Instagram: @chemistrylab110
#Greenland #Iceberg #Melting
Project Idea
Melting icebergs impact marine ecosystems by releasing freshwater and sediments into the surrounding seawater. The added freshwater alters the density of the seawater, which changes how the water flows and mixes. Sediments may contain nutrients and they can change the optical properties of the seawater, both of which can impact the productivity of photosynthetic organisms. Our understanding of iceberg melt is based on limited observations and overly simplistic models. The project will study iceberg melt and its impacts on marine ecosystems in Greenland and Antarctica.
How does the KT Boost Fund support you and your project idea?
The fund will enable an international group of early-career researchers to conduct a 3-week expedition to Greenland to study iceberg melt that will also provide training and educational opportunities for undergraduate and graduate students. The expedition is a unique opportunity to apply novel techniques to better understand ice-ocean interactions that would not happen without contributions from the Fund.
If I had more time for things other than research I …
…would write science fiction novels.
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Name: Dr. Daniel Carlson
Research field: Oceanography
Institution: Helmholtz-Zentrum Hereon, Institute of Coastal Ocean Dynamics, Oceanography
Web: Personal Website
ResearchGate: Daniel Carlson
Twitter: @OceanYodeller
#Structural virology #Human cytomegalovirus #Cellular cryo-electron tomography
Project Idea
Being obligatory intracellular parasites, viruses infect a specific host and hijack the cellular machinery to replicate themselves. With cryo-electron tomography, I aim at investigating virus-host interactions at the molecular resolution and in native state directly inside infected cells. Human cytomegalovirus is the first cause of congenital birth defect in industrialized countries and here, we will elucidate key aspects of virus replication, assembly and persistence by focusing on the remodelling of cellular organelles and the 3D reorganization of the intracellular space late in infection
How does the KT Boost Fund support you and your project idea?
Thanks to the Klaus Tschira Boost Fund, I can develop further my own line of research on “Organelle remodelling as a platform for Human Cytomegalovirus assembly” and foster international collaborations. This independent funding gives me also access to state-of-the-art facilities and the possibility to recruit my own students. The expected findings of the proposed research are likely to pave the way for more targeted research on the molecular mechanisms at play as well as applied studies for the development of new vaccines, antiviral drugs and control measures against human cytomegalovirus.
If I had more time for things other than research I …
…would like to do millions of things including voluntary work in associations, mentoring students, reading books, do sports, cook, bake, travel and most importantly spend more time with my family.
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Name: Dr. Emmanuelle Quemin
Research field: Structural virology
Institution: HPI Leibniz Institute for Experimental Virology / Centre for Structural Systems Biology / Structural Cell Biology of viruses
Web: HPI- Structural Cell Biology of Viruses
#Pathogen genomics #Evolution #Ancient DNA
Project Idea
Despite the dramatic impact of infectious diseases on human evolution, we have little understanding about their origin. We believe spillover events from domesticated animals during the agricultural transition starting around 10,000 years ago gave rise to many major human pathogens today. Here we set out to find ancient DNA of infectious pathogens in the remains of prehistoric domesticates and humans. We aim to reconstruct the genomes of ancient pathogens, elucidate their prehistoric reservoir and understand the genetic changes behind the spillover.
How does the KT Boost Fund support you and your project idea?
I am fascinated by ancient DNA and the unprecendented insights such genetic time travel can provide. Ancient DNA research is truly interdisciplinary, combining vastly different exptertise ranging from molecular biology and computational data analysis to archaeology and history. The KT Boost fund provides me the pivotal funding necessary to accommodate the expertise in my young lab as well as finance the costly data generation necessary to take on this project.
If I had more time for things other than research …
There is nothing better than grabbing my three kids on the weekend and take them out into the wild. It helps the whole family to reset and stay sane in the midst of our fast paced daily life.
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Name: Dr. Felix M. Key
Research field: Evolutionary genetics
Institution: MPIIB Max Planck Institute for Infection Biology
Web: Key Lab
Twitter: @fm_key
#Quantum Field Theory #Gravity #Symmetries
Project Idea
Three of the four fundamental forces in Nature are beautifully captured by the framework of quantum field theory. Within this framework predictions for scattering experiments at particle colliders rely on the knowledge of certain mathematical building blocks, so-called Feynman integrals. Their analytical understanding, however, is currently limited to the simplest examples. It is the aim of this project to explore new hidden symmetries of these integrals. In particular, it will focus on the recent discovery of similar structures in the context of the fourth fundamental force, gravity.
How does the KT Boost Fund support you and your project idea?
The funding provided by the Boost Fund will help paving the way for understanding the connections between established quantum field theory methods for scattering amplitudes and theoretical predictions for gravitational wave physics. Together with my collaborators, who will be supported by the Boost Fund, we will focus on new symmetries in Einstein’s theory of gravity and on exploiting resulting constraints for interacting black hole systems. Insights into the mathematical structure of elementary particle physics and new relations to the theory of integrable models are to be expected.
If I had more time for things other than research I …
… would spend most of it with my family and distribute the rest among photography, gardening and sports.
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Name: Dr. Florian Loebbert
Research field: Theoretical Particle Physics
Institution: University of Bonn/ Bethe Center for Theoretical Physics
Web: BCTP Bonn
#Air quality #Atmospheric chemistry #Urban emissions
Project Idea
The quality of the air we breathe is largely affected by anthropogenic emissions. Volatile chemical products that include emissions from personal care products, cleaning agents, coatings, as well as other everyday chemical products have immerged as one of the largest urban emission source of gas-phase organic compounds. In this project we will identify their potential to form ozone and particulate matter, two of the most relevant pollutants for health impacts. This will be achieved by performing ambient measurements in the US onboard an aircraft and in Germany using a mobile laboratory.
How does the KT Boost Fund support you and your project idea?
The Klaus Tschira Boost Fund will be an ideal first milestone towards establishing my own research ideas and becoming a leading scientist in the field of atmospheric air pollution. Funding will be used to expand my collaborations by participating in one of the largest aircraft missions to understand urban and marine air pollution in the US called AEROMMA (https://csl.noaa.gov/projects/aeromma/). The gained expertise from this mission will then be used to develop my own experimental setup for air quality measurements in urban environments across Europe.
If I had more time for things other than research I …
… would travel more, especially at remote places close to the ocean where I could enjoy spearfishing, the silent beauty of the deep ocean, colourful sunsets, and the sound of waves while falling asleep.
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Name: Dr. Georgios Gkatzelis
Research field: Atmospheric Chemistry
Institution:Institute of Energy and Climate Research, IEK-8: Troposphere, Forschungszentrum Jülich GmbH
Web: Organic Trace Gases Group
Twitter: @GGkatzelis
LinkedIn: Georgios Gkatzelis
#Molecular networks #Computational analysis #Drug response prediction
Project Idea
Networks are used to mathematically represent and computationally analyze complex processes. We develop mathematical and algorithmic approaches to investigate the huge networks arising from the highly complex system of human body cells. These are composed of millions of different, interacting molecules. During disease, molecular functioning is disturbed. Which drug can help? We develop software tools to derive predictions on that question based on large molecular networks. We consider different conditions, e.g. cancer subtypes, or age, and use molecular data including peptides and transcripts.
How does the KT Boost Fund support you and your project idea?
The funding enables me to team up with a postdoctoral researcher and a student research assistant to leverage our interdisciplinary expertise of computer science and mathematics for a medically relevant problem. With joint forces, we can bring our solutions into a usable format for a broad audience within short time. In addition, I can gather first experience leading a research team. The project strengthens my profile as established and independent scientist in the field of network-based analysis and thus helps me on my path towards a permanent leadership position in research.
If I had more time for things other than research I …
… would practice soccer tricks to show my sons, play volleyball and go swimming more often, play more card or board games with my family, read more books, learn a new language and to play the guitar, …
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Name: Dr. Katharina Baum
Research field: Network-based data analysis
Institution: Data Analytics and Computational Statistics, Hasso Plattner Institute, Digital Engineering Faculty, University of Potsdam
LinkedIn: Katharina Baum
Matthew Agler
#Plant microbiomes #Microbial interactions #Microbial ecology
Project Idea
Plant pathogens can be devastating, causing major annual losses to crop yields. Interestingly, potential pathogens can often be readily isolated from perfectly healthy tissues in wild plants. How is this possible? Theory predicts virulence is mainly determined by host and pathogen traits, but the rich microbial communities on plants have often been observed to play important roles. Here, I aim to study the role of metabolic cross-feeding between commensal bacteria and potential pathogens to determine whether and how it favors reduced virulence of pathogens.
How does the KT Boost Fund support you and your project idea?
If we can better understand how cross-feeding influences pathogen virulence, it would possible to influence it by plant breeding. Thus, I believe this research has potential to open new approaches to sustainably combat plant diseases and control plant microbiomes. The Klaus Tschira Boost fund will enable me to hire a postdoctoral scientist and to diversify our approach and drive our research in this direction. Personally, the funding to jumpstart a new and novel research direction and to build and strengthen collaborations represents an important step toward an independent career in academia.
If I had more time for things other than research I …
… would keep spending lots of time with my family, but it would be much more focused on them and valuable! I would also spend more time outdoors, where I find it is easiest for me to think.
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Name: Dr. Matthew Agler
Research field:Microbial ecology and Plant-microbe interactions
Institution: Friedrich Schiller University of Jena/ Department of Microbiology
Web: The Plant Microbiosis Lab
Twitter: @aglernino
#Mosquitoes #Viruses #Interactions
Project Idea
Often considered as the deadliest animals on earth, mosquitoes owe their bad name to the dangerous microorganisms they transmit, including viruses like Dengue. Mosquitoes also host viruses that are not transmitted to humans, called insect specific viruses. Insect specific viruses share the same host environment with mosquito-borne pathogens and can interfere with their transmission to other animals. As such, they can be used to control mosquito-borne diseases although the mechanisms behind these interactions are unknown. My project aims to understand how microorganisms in mosquitoes interact.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund will significantly contribute to my academic career by enabling me to lead my first independent research project within my host institute. This project will be a first step to create my line of research. Without the KT Boost Fund, it would be impossible to focus on a more fundamental side of the vector ecology research. At the moment, this is not the main focus of my current funding as a post-doctoral researcher. The KT Boost Fund will also allow me to establish my own collaborations and help me build my network.
If I had more time for things other than research I …
… would train for a marathon. I run long distances but it is difficult to find the time to train consistently. I would sing and play ukulele more. I also want to become fluent in German one day 🙂
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Name: Dr. Mine Altinli
Research field: Molecular Entomology
Institution: Bernhard-Nocht Institute for Tropical Medicine
Web: Schnettler Group
Google Scholar: Mine Altinli
Twitter: @mine_altinli / @BNITM_de
#Brain connectivity #Polarimetry #Light scattering
Project Idea
Studying the function of the brain requires precise knowledge about its nerve fiber architecture. 3D-Polarized Light Imaging reconstructs 3D nerve fiber tracts in whole brain sections, but leaves uncertainties in pixels containing crossing fibers. The recently developed technique Scattered Light Imaging reconstructs crossing nerve fiber pathways with micrometer resolution. In this project, we will build a Scattering Polarimeter that combines both techniques in one system, enabling multi-modal imaging of brain tissue and providing unprecedented insights into the brain’s nerve fiber network.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund empowers me to bring my recently developed neuroimaging techniques into practice. It allows me to purchase high-quality equipment for a new imaging system, showcase my research at international conferences, and start new collaborations. It gives me the necessary freedom, time, and support to realize my own ideas and establish my own field of research. With my own independent funding, I can hire a PhD student and start building my own research group – a first decisive step in my scientific career towards an established, independent position in academia.
If I had more time for things other than research I …
… would travel around the world and get to know other cultures – there is so much to see! Back home, I would spend more time on my hobbies such as playing music, hiking, ballroom dancing, and painting.
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Name: Dr. Miriam Menzel
Research field: Neuroimaging
Institution: Forschungszentrum Jülich, Institute of Neuroscience and Medicine (INM-1)
Web: Fibre Architecture Group / Personal Profile
ResearchGate: Miriam Menzel
Christian Hering-Junghans
Claudia Alfes-Neumann
Marcel Pawlowski
Merle Röhr
Paola Carrillo-Bustamante
Pauline N. Fleischmann
Penelope R. Whitehorn
Romy Lorenz
Sabine Becker
Walter Bronkhorst
Wilhelm Palm
Christian Hering-Junghans
Project Idea
Semicunducting materials play a major role in modern society as they enable miniaturization of electronics and therefore fuel our interactive lifestyle. Some of these materials are combinations of triele elements (Al, Ga, In) with pnictogens (P, As, Sb) and their production is challenging. We investigate the fundamental reactivity of tripnictanes Pn3R3 (Pn = P, As), for example as a tool to selectively make molecular precursors to semi-conducting materials by selectively providing the pnictogen part. A compound known as Salvarsan, was the first cure for syphilis and its major component is believed to be a triarsirane As3R3. We seek to selectively make the active ingredient of Salvarsan, solving a mystery that is over 100 years old.
How does the KT Boost Fund support you and your project idea?
How does the KT Boost Fund Having a postdoctoral researcher will allow us to diversify the research program further beyond our initial objectives. In addition, the KT Boost fund will give us the opportunity to strengthen existing national and international collaborations on the chemistry of triphosphiranes, by sending student research assistants to work in the laboratories of our collaborators. The KT Boost fund will allow me to dedicate more of my time into the training of student research assistants and to actively work towards my habilitation through diversification of my research program. I am looking forward to be part of the KT fellow’s network, thus, giving me the opportunity to engage with a wider community to broaden my horizon, personally and professionally.
If I had more time for things other than research I …
… would spent more time with my wife and two children in the wilderness and dive more into landscape photography.
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Name: Dr. Christian Hering-Junghans
Research field: Inorganic Chemistry / Catalysis
Institution: Leibniz Institute for Catalysis Rostock (LIKAT)
Web: www.chj-photography.com (personal),
www.catalysis.de (institutional)
Twitter: @hering_lab
Project Idea
In the project I will investigate implications of the theory of certain modular forms for the number of rational points on elliptic curves. Elliptic curves are given by solutions to equations of the form E : y2 = x3 + ax + b, where a and b are rational. The complex points of such objects have a very appealing form: they look like donuts! Particularly interesting are the rational points of E which can be compared to the “sprinkles” on the donut. When proving Fermat’s Last Theorem Andrew Wiles confirmed a far-reaching correspondence between modular forms and elliptic curves. In the project, I will investigate the theory of certain generalizations of such modular forms and their implications for the number of rational points on elliptic curves.
How does the KT Boost Fund support you and your project idea?
The fellowship of the Klaus Tschira Boost Fund enables me to start building up my own research group and will help me to grow into the role of a successful group leader and mentor for young researchers. As my project is located at the interface of different areas of mathematics exchanging ideas with fellow researchers and collaborations are crucial for its success. The funding of the Klaus Tschira Boost Fund will give me the necessary time and freedom to enlarge, establish and use my national and international network to collaborate on my project.
If I had more time for things other than research I …
… would spend a lot more time doing sports with my son and by myself. I would like to go mountainbiking with my son more often, train for a marathon and maybe even resume my triathlon career and train for an Ironman.
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Name: Prof. Dr. Claudia Alfes-Neumann
Research field: Pure mathematics (number theory, automorphic forms, L-functions)
Institution: Bielefeld University, Faculty of Mathematics
Web: www.claudia-alfes.de; www.uni-bielefeld.de
Project Idea
Major galaxies like our Milky Way are surrounded by swarms of smaller satellite galaxies. Our leading cosmological models predict that the distribution and motion of such satellites should be rather random. Instead, several observed systems show surprising degrees of order: the satellites are preferentially distributed and move along flattened structures. These ‘Planes of Satellite Galaxies’ fundamentally challenge our understanding of cosmology and galaxy formation. I will study systems of satellite galaxies in a range of cosmological simulations, to determine the occurrence, properties, and origins of satellite planes, and determine whether they can tell us something about the properties of the host galaxy or the nature of Dark Matter.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund will help me widen the scope of my work on satellite galaxy systems and their phase-space correlations, enabling a more comprehensive study into this topic than possible thus far. For example, it provides me with the necessary independence to not only focus on the established cold dark matter paradigm, but also investigate alternative dark matter models. In addition, it will support several novel aspects that are not easily funded by traditional means. This includes a hackathon-like workshop to bring together experts in different fields to develop and work on collaborative projects, and professionally produced outreach materials to support my passion for science communication and the dissemination of my results.
If I had more time for things other than research I …
… would work on my photography, especially on editing the many photos I collected in the past years. I became quite active in street photography during my time in the United States – an excellent way to discover and document both the exceptional and the ordinary in everyday life – but accumulated a substantial backlog of photos which deserve to be properly edited and turned into a publication or exhibition. Of course I’d also love to get back to actually taking more pictures, both around home as well as on trips, and to find more time to study my ever-increasing library of photo books.
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Name: Dr. Marcel S. Pawlowski
Research field: Astronomy/Astrophysics
Institution: Leibniz Institute for Astrophysics Potsdam
Web: http://marcelpawlowski.com (professional),
http://8minutesold.com (personal)
Twitter: @8minutesold
LinkedIn: Dr. Marcel S. Pawlowski
Merle Röhr
Project Idea
Nature covers its entire energy requirements from sunlight, having developed robust and efficient light-collecting machineries in an evolutionary process over millions of years. A detailed understanding of the natural light-harvesting processes would make nature’s design principles available for the development of new materials. Scientifically, light-harvesting is a physical process that requires a quantum-mechanical treatment, which is not a intuitive. We wish to bring quantum information into a microscopic, atomistic picture, allowing to turn it into clear synthesis strategies. This project focuses on a particularly fascinating and efficient example of natural light-harvesting systems: The Chlorosomes of green sulfur bacteria.
How does the KT Boost Fund support you and your project idea?
The Klaus Tschira Boost Fund allows me to bring together our expertise in the atomistic description of quantum-mechanical properties of molecular aggregates with experts from biology and spectroscopy. It provides financial means to establish an international cooperation and to lead an interdisciplinary project, spanning contributions from biology, chemistry and physics. With the funding of a PhD student, the Fund allows us to transfer our knowledge to the investigation of living matter, building the prerequisites for entering the field of Quantum Biology.
If I had more time for things other than research I …
… would take the chance to get more sleep (I have a 1 year old daughter) and to write a book portraying the life of my professor who taught me quantum mechanics. Her biography has always been an inspiration to me.
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Name: Dr. Merle I. S. Röhr
Research field: Computational Chemistry, Theoretical physics, Quantum biology
Institution: Center for Nanosystems Chemistry, Julius-Maximilians Universität Würzburg
Web: Roehr Group, Software Project
Paola Carrillo-Bustamante
Project Idea
Mosquitoes transmit dangerous diseases like malaria and dengue fever, making them one of the most dangerous animals on earth. Their life cycle starts in water, where larvae are highly vulnerable to environmental factors such as changes in pH, temperature, and nutrients. In an ideal breeding site, most larvae survive creating large populations of adult mosquitoes, and thus, a high potential for disease transmission. Climate change will have an impact on these breeding sites; how will it affect the dynamics of mosquito populations and disease transmission? Here, I aim to identify which environmental factor is most important for larval growth, and simulate how these environmental changes shape the transmission dynamics of several diseases.
How does the KT Boost Fund support you and your project idea?
The novelty of this research is to study the growth of several mosquito species simultaneously and predict how climate change will affect the spread of many mosquito-borne pathogens. For this purpose, experiments will be executed in Ecuador, a region that is highly relevant for the study of these diseases. Without the Klaus Tschira Boost Fund this will simply not be possible.
Additionally, thanks to this funding, I have now the opportunity and freedom to lead this transnational and interdisciplinary project, representing a new exciting challenge in my scientific career.
If I had more time for things other than research I …
… would teach more. One of my goals is to make a theoretical biology curriculum for undergrad students. I would also love to cook all the recipes from my Jamie Oliver and Otto Lenghi books. And actually, since I recently became a mother, I now dream of a long yoga retreat in Bali.
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Name: Dr. Paola Carrillo-Bustamante
Research field: Computational Biology / infectious diseases
Institution: Max Planck Institute for Infection Biology
Research Gate: Paola Carrillo-Bustamante
Project Idea
When Cataglyphis desert ants leave their nest for the first time, they perform explorative trips to acquire all information necessary to become successful foragers. During these learning walks, the ants frequently look back to the nest entrance to memorize their homing direction. At the end of my doctoral project, my field team and I showed that they align their gaze-directions using the earth’s magnetic field. I hypothesize that the ants’ magnetic compass is a light-independent, active sensor in the ant antenna. To test these hypotheses, I plan to conduct behavioral experiments under natural and experimentally altered magnetic conditions in our field site in Greece, and neurobiological experiments in the laboratory in Würzburg.
How does the KT Boost Fund support you and your project idea?
By providing support for my project, the KT Boost Fund enables a novel research approach that is to record antennae postures of freely moving ants performing a navigational task in the natural habitat for the very first time. The recent development of camera techniques and the increase of computational power make such an approach now possible. The envisaged field experiments will lead to a better understanding of magnetoreception. In addition, I aim to make progress on the neurobiological level, which is indispensable to resolve the underlying mechanisms. Last, but not least, the fellows’ network will provide manifold exchange possibilities across disciplines. I look forward to getting new perspectives and to sharing my experiences.
If I had more time for things other than research I …
… “If I had fifty-three minutes to spend as I liked, I should walk at my leisure toward a spring of fresh water” says the Little Prince. I totally agree with him. In my favourite scenario, this spring would be located in an oasis, for example in the Sahara, the Namib Desert or any desert in Australia – all places that I want to (re-)visit. In the best case, I would have a great book in my backpack that I would read without any interruptions.
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Name: Dr. Pauline N. Fleischmann
Research field: Neuroethology
Institution: University of Würzburg, Biocenter, Zoology II (Behavioral Physiology and Sociobiology)
Twitter: @Cataglyfilosofi
Web: www.biozentrum.uni-wuerzburg.de
Project Idea
Bumblebees are really important pollinators in both farming and natural ecosystems but recently they have been suffering from large population declines. Climate change is partly responsible and, as temperatures continue to rise, scientists predict this will have serious consequences for bumblebees. However, the actual ways in which warmer temperatures are harming bees is not so well understood. One mechanism may be direct impacts on hibernation, a key stage in the bumblebee life cycle, as warmer temperatures may reduce the survival of queens by depleting their fat reserves more rapidly. This project aims to find out by investigating the survival of hibernating bumblebee queens in the field under different climatic conditions.
How does the KT Boost Fund support you and your project idea?
My current, desk-based research uses existing data and integrated modelling to investigate the interactions among bumblebees, land use and climate change in Europe. This will greatly benefit from complementary field research to provide direct empirical evidence for climate change impacts on bumblebees. The KT Boost Fund offers the ideal financial and professional support, allowing me to develop a new, independent research project in this area. Support from the fund will also allow me to develop a collaborative network, forging new links with scientists working with pollinators across Europe. Further, I will be able to attend important conferences, which will be help with successful dissemination of the results.
If I had more time for things other than research I …
… would spend more time drawing. In another life Natural History illustration would have been a wonderful profession!
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Name: Dr. Penelope R. Whitehorn
Research field: Pollinator Ecology
Institution: Institute of Meteorology and Climate Research Atmospheric Environmental Research (IMK-IFU), Karlsruhe Institute of Technology (KIT)
Web: Land Use Change & Climate Research Group
Project Idea
The powerful abilities of humans to solve problems, learn and memorize have made us successful as a species. Brain scanning helped us to understand that such intelligent behaviour is supported by a set of brain regions known as the frontoparietal cortex. This cortex consists of different layers. However, limitations in standard brain scanning prevents us to “zoom” in enough on the brain, contributing to our lack of insight into how the different layers contribute to intelligent behaviour. Here, I will develop a new method to tackle this problem. I will combine ultra-sensitive brain-scanning (with sufficient “zoom”) with an intelligent real-time algorithm, allowing me to quickly map out a layer’s specific role in intelligence.
How does the KT Boost Fund support you and your project idea?
In 2018, I took up a 4 year-long personal fellowship for my research project aiming at understanding the unique functional role of subsystems in the frontoparietal cortex. My proposal to the KT Boost Fund grew out as a natural continuation of this project while at the same time being intellectually confronted with limitations of current brain scanning technology and grasping the enormous potential of ultra-sensitive brain scanning (i.e., 7T fMRI). The KT Boost Fund allows me, for the first time (as my personal fellowship does not entail money for recruiting staff), to employ a highly qualified postdoctoral researcher to work on this ambitious and innovative project full time – the beginnings of my own lab.
If I had more time for things other than research I …
… would do a deep dive into neuroanthropology – study embodied cognition across different cultures combining “first-person” (e.g., microphenomenological interview techniques) and “third-person” approaches (e.g., eye tracking, heart rate, EEG). In addition, I would love to study art history and spend some months in a meditation cave 🙂
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Name: Dr. Romy Lorenz
Research field: Cognitive neuroscience, neuroadaptive technology, machine learning, ultrahigh-field functional brain imaging
Institution: Max Planck Institute for Human Cognitive and Brain Sciences – Department of Neurophysics
Web: www.romylorenz.com
Twitter: @romy_lorenz
Project Idea
Metal ions are crucial for all living organisms. They do not only ensure proper protein and enzyme function but also, do play a fundamental role in signaling such as synaptic transmission. Perturbances of these processes can lead to severe (neurodegenerative) diseases. Together with researchers from different disciplines, we seek to shed light on these still only poorly understood neuronal processes. We are focusing on zinc and its role in the transmission and processing of sensory information in the central nervous system. Therefore, we are developing specialized fluorescent sensors that upon zinc binding exhibit a fluorescent signal, which allows us to study the trafficking of zinc on a molecular level in live cells.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund makes an essential contribution to the establishment of this interdisciplinary research field in my research group. We are now able to purchase the necessary equipment and to fund a PhD position. Also, the KT Boost Fund enables us to foster national and international collaborations. With the expertise of researchers of different backgrounds, we will be able to investigate the role of zinc ions in synaptic transmission in a unique and extensive way, which will increase our knowledge about these fundamental neuronal processes. In addition, all team members working on this project, will gain experience in working in interdisciplinary fields and thus increase the awareness for the importance of interdisciplinary work.
If I had more time for things other than research I …
… would travel more and together with my husband, explore nature and other cultures. Back home, I would focus more on my hobbies such as reading, crafting, painting and gardening. I probably would set up a huge garden – big enough to maybe even host a couple of alpacas.
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Name: Jun.-Prof. Dr. Sabine Becker
Research field: Metalloneurochemistry
Institution: Technische Universität Kaiserslautern
Web: www.chemie.uni-kl.de/ag-becker/
Project Idea
The development of a vertebrate embryo into a full-grown animal is a fascinating and tightly orchestrated process. Elegant work from the past has, for example, shown that the temporal and spatial regulation of gene expression controls embryonic patterning and polarization. In turn, gene expression itself is subject to epigenetic regulation via methylation of DNA and histones, adding yet another layer of complexity. However, how gene expression is controlled by RNA modifications during embryonic development remains largely elusive. In our project “ How does m6A modification on mRNA affect embryonic development in zebrafish? ” we will study how dynamic changes in m6A mRNA modifications controls gene expression during vertebrate development.
How does the KT Boost Fund support you and your project idea?
The independent funding from the KT Boost Fund supports me to start my own line of research into the field of RNA modifications. With the funding I am now able to hire a full-time technician for two years who will support me in the lab. The proposed research covers a variety of techniques in a collaborative environment. With these collaborations I hope to establish my own network, which will be extremely important to start my independent research group. With the funding from the KT Boost Fund, I now have the opportunity to further shape my future research line in which I aim to study phase-separation processes as well as RNA modifications during zebrafish development
If I had more time for things other than research I …
… would spend even more time with my family, which was very recently extended. We now have two daughters, Nova of 3 years old and Fiene who is just 2 weeks old. To ‘escape’ from all the ladies at home, I might want to go out for a run more often.
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Name: Alfred Willem (Walter) Bronkhorst, PhD
Research field: Developmental Biology (with a focus on germ cells) & RNA Biology
Institution: Institute for Molecular Biology, Mainz. Ketting Lab.
Web: www.imb-mainz.de
Project Idea
The cells in our body tightly regulate the acquisition and usage of nutrients to match their metabolic demands. For example, a growing cell increases nutrient uptake to build new mass, whereas a starving cell taps into alternative nutrient sources to survive. We are particularly interested in the ability of cells to eat proteins and break them down into their constituent amino acids. In this project, we will develop analytical mass spectrometry methods to investigate how cells generate amino acids from extra- and intracellular protein pools. We hope that the results will characterize proteins as an important nutrient source for our cells, which is exploited by cancer cells to thrive in tumors with poor blood supply.
How does the KT Boost Fund support you and your project idea?
Funding by the Klaus Tschira Boost Fund will allow us to develop state-of-the-art methodology to quantify metabolic outputs of the different pathways through which cells digest proteins from diverse sources. This will allow us to move early on into a research area that, despite high relevance for the metabolism of normal and transformed cells, used to be neglected due to the traditional focus on canonical nutrients such as glucose and free amino acids. The network of the Klaus Tschira Boost Fund will create many opportunities for scientific exchange and allow me to be part of an interdisciplinary peer group, which will be intellectually stimulating and support my development as a scientist.
If I had more time for things other than research I …
… would spend more time at concerts and the opera. I have been dreaming about a visit to the Bayreuth Festival for quite some time now.
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Name: Dr. Wilhelm Palm
Research field: Cell Biology, Metabolism, Cancer
Institution: German Cancer Research Center (DKFZ)/ Cell Biology and Tumor Biology Program/ Cell Signaling and Metabolism Group
Web: www.dkfz.de (Junior Research Group Cell Signaling and Metabolism)
Darjus Tschaharganeh
Dermot Harnett
Florian I. Schmidt
Jan Rennies-Hochmuth
Julia Grosse
Lena J. Daumann
Lysanne Snijders
Matthias Schröter
Nadja Klein
Patrina S. P. Poh
Tuan Leng Tay
Project Idea
Most, if not all, human diseases are caused by genetic changes. Although researchers now know the underlying genetic changes associated with respective diseases, functional validation of these changes is still crucial to directly attribute genotypic changes to phenotypic outcomes. In this project we will establish and in vivo platform for RNA editing based on the recently described CRISPR/Cas13 system. We will develop tools for inducible RNA editing, benchmark this system for in vivo use, and perform first proof of concept studies. The ultimate goal of this project is to generate new RNA editing technology, which will be distributed to the research community, to make it accessible for a broad use in different scientific disciplines.
How does the KT Boost Fund support you and your project idea?
My project is risky but could hold great promise for future applications in various disease models or even in therapeutic applications. The flexibility and the possibility to pursue risky projects by the Klaus Tschira Boost Fund will have tremendous value for successful execution. Additionally, it will boost our visibility on an international level and foster new collaborative relationships. I anticipate that the Klaus Tschira Boost Fund will also help us in connecting and distributing this technology to other researchers, building an international network around the technology and their users. I am particular excited about the possibility to join an Alumni network through the Klaus Tschira Boost fund for exchanging ideas and experiences.
If I had more time for things other than research I …
… would like to be closer to nature. One dream would be to have a vineyard, where I could take care of the grapes and make my own wine.
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Name: Dr. Darjus Tschaharganeh
Research field: Cancer Research
Institution: Helmholtz University Group / “Cell Plasticity and Epigenetic Remodeling” / German Cancer Research Center
Web: Deutsches Krebsforschungszentrum
Twitter: @tschaharganeh
Project Idea
Each of a complex brain’s billions of cells has a single ancestor. This cell’s many, varied ancestors divide, migrate and differentiate into their final forms because each of them contains a characteristic set of molecular machines – proteins – that determine cell behavior and identity. A cell’s proteins are ‘expressed’ from a specific subset subset of the instructions (genes) in it’s DNA, with genes first being ‘transcribed’ into an intermediate form – RNA – and then ‘translated’ into protein. My project quantifies these two processes over time in the developing mammalian cortex, with the aim of determining their influence on final protein levels, and hence the form and function of the brain.
How does the KT Boost Fund support you and your project idea?
Our data comprise millions of data points, simultaneously measuring gene expression over five timepoints at the level of RNA, DNA and protein. Unlike most data – our system is not in equilibrium, so that modelling it accurately requires nonlinear modelling of degredation kinetics. Thanks to the KT Boost Fund I have the time and autonomy to develop the unique computational tools required to do this, unlocking insights into the mechanisms of gene regulation that a surface level ‘out of the box’ analysis would miss.
If I had more time for things other than research I …
… I would spend more time playing music and traveling. As an amateur guitarist I try to make up in enthusiasm what I lack in talent and practice time. I also love to travel, and experience other cultures. Having travelled in Asia and South America, Africa would be next on my list.
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Name: Dr. Dermot Harnett
Research field: Computational Biology
Institution: Humboldt University of Berlin/ Berlin Institute for Molecular Systems Biology
Florian I. Schmidt
Project Idea
Our project aims to shed light on inflammatory responses that secure an intact cell barrier to separates the content of our intestinal tract from the rest of the body. Such responses are critical to fight pathogens, but can also overshoot and cause disease. Since the properties of these intestinal cells cannot be recapitulated in standard cell culture conditions, we grow 3D ‘mini guts’ derived from human intestinal stem cells. Using alpaca-derived antibodies as well as novel probes, we will investigate how specialized molecules in ‘mini guts’ detect infections with viruses such as noroviruses. We will try to reveal how signalling complexes termed inflammasomes coordinate responses that help eject infected cells and curtail virus spread.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund allows my lab to interact with the best scientists worldwide, learn the requisite techniques, and make the necessary investments to enter an emerging field of cell biology, in which cellular processes are recapitulated in 3D ‘organoid cultures’. These recapitulate the complexity of human tissues better than traditional cell cultures techniques. We can thus be among the first to study inflammatory responses of specialized gut cells in the most physiological models of human cells. PhD students in my lab will thus be able to attend conferences and methods courses, invite collaborating experts, and develop ground-breaking new techniques that will allow us to visualize inflammation in real time or in molecular resolution.
If I had more time for things other than research I …
… would dig through archives and trace back the history of my family all over Europe, volunteer in Archeological excavations, travel to learn more about culture or nature around the world … or finish setting up our apartment (we only moved in two years ago).
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Name: Dr. Florian I. Schmidt
Research field: Innate Immunity, Cell Biology, Virology, Nanobody engineering
Institution: University of Bonn, Institute of Innate Immunity, Research Group Molecular Immunology
Web: The Schmidt Lab; Core Facility Nanobodies; Researchgate
Twitter: @FISchmidtLab
Project Idea
Noise, reverberation and hearing loss can significantly hamper our speech communication. Despite a long history of research on speech intelligibility and the development of various models for predicting human speech recognition, the underlying functional mechanisms are not yet fully understood. This project aims to better understand how we perceive speech in complex listening conditions and especially how we combine information across the two ears. Several auditory experiments will be conducted with normal-hearing and hearing-impaired listeners to extend the existing knowledge on what creates effortful listening, and to lay the foundation for improved prediction models and applications in, e.g., hearing aids and communication systems.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund will be a significant contribution to my professional future. Just coming back from a fascinating post-doc year in Boston, I have started building a solid base and international network for a scientific career. The support will create the necessary freedom – both in terms of resources and time – to continue working on basic research projects with high potential for publications while, at the same time, carrying on the development of my group at Fraunhofer IDMT. In particular, I will be able to foster international research collaborations, to strengthen my publication record to eventually fulfil the formal requirements of a habilitation, and to significantly increase my visibility both on a national and international level.
If I had more time for things other than research I …
… would spend more time on the many things that have to be balanced out in the every-day routines. First and foremost, I would involve more into the developing hobbies of my two daughters (3 and 7 years), who start going to football classes and begin other activities – fascinating times! I might even resume my activities as youth coach. And then there would be reading, traveling, restarting my tennis and badminton activities – if only there was more time …
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Name: Dr. Jan Rennies-Hochmuth
Research field: Speech perception in normal-hearing and hearing-impaired listeners
Institution: Fraunhofer-Institute for Digital Media Technology IDMT / Hearing, Speech and Audio Technology, Oldenburg, Germany
Web: www.idmt.fraunhofer.de
Project Idea
Tiny algae in the ocean are responsible for half of the global CO2 uptake (photosynthesis) and it is widely believed that for most microalgae photosynthesis is the only source of energy and carbon. But, there are microalgae classified as mixotrophs, who can switch between photosynthesis and using organic food, for example by eating bacteria. Once considered oddballs, there is increasing evidence that this dietary mode is very prominent. The project will characterize the contribution of mixotrophs to the microalgae community in the Baltic Sea over an annual cycle. Additionally, the project will allow research to the Arctic Ocean investigating mixotrophs during polar day and night, when light conditions contrast with 24h light and darkness.
How does the KT Boost Fund support you and your project idea?
Contributions of the fund will address critical questions on feeding modes in microalgae communities, which provide the base of marine food webs and can therefore imply consequences as far reaching as fishery production to secure human food supply. The Klaus Tschira Boost Fund will provide the opportunity to conduct small-scale studies over a wide range of seasonal and spatial scales that are expected to have a large scientific impact in the field aquatic sciences. Alongside a field study in the Baltic Sea, the project partially revolves around national and international collaborations to obtain samples from different field campaigns planned for 2019-2020 in the Arctic Seas.
If I had more time for things other than research I …
… would travel the Pan American Highway all the way from Alaska to Argentina.
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Name: Dr. Julia Grosse
Research field: Marine Biogeochemistry
Institution: GEOMAR Helmholtz Centre for Ocean Research Kiel, Germany
Marine Biogeochemistry Division, Biological Oceanography Group
Web: ResearchGate; Changing Arctic Ocean
Project Idea
Lanthanides (Ln), the group of elements from lanthanum to lutetium, are indispensable for all technologies used in our daily lives. Surprisingly, certain bacteria require these elements for growth, and remarkably, the biological role of the lanthanides has been known for less than a decade. The naturally occurring actinides thorium and uranium are commonly found together with lanthanides in ores and some actinides that are a result of nuclear reactor processes, have similar ionic radii to the early, trivalent lanthanides. Our project “Interaction of lanthanide-dependent bacterial proteins with actinides” will explore whether actinide elements can bind and replace lanthanides in the active sites of Ln-proteins.
How does the KT Boost Fund support you and your project idea?
The Klaus Tschira Boost Fund allows me to bring together my group who is working on elucidating the mechanisms and metal binding properties of lanthanide dependent proteins with microbiologists Prof. Huub Op den Camp, Radboud University, Netherlands and Prof. Cecilia Martinez-Gomez, Michigan State University, USA, and well as with spectroscopist Dr. Robin Steudtner (Helmholtz-Zentrum Dresden-Rossendorf, Germany) and radiochemist Prof. Georg Steinhauser (IRS Hannover, Germany). We will be able to buy specialized equipment, isotopes, pay for a PhD student and cover travel expenses with the Klaus Tschira Boost Fund to conduct this international and interdisciplinary project together.
If I had more time for things other than research I …
… would write a chemistry related cookbook and travel more!
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Name: Prof. Dr. Lena J. Daumann
Research field: Bioinorganic Chemistry
Institution: Ludwig-Maximilians-Universität München
Web: www.cup.lmu.de
Project Idea
With a little help from my friends: Guppies live in the rainforest streams of Trinidad, a dynamic environment in which feeding opportunities change quickly. This makes Trinidadian guppies an ideal study system to find out how animals deal with environmental uncertainty when looking for food.
I previously discovered that individual guppies are consistently better in finding food when they are more social. With support of the KT Boost fund, I can now further explore how exactly the guppies achieve this and if certain types of guppies are more likely to be more social. Individuals of the same species often differ in how social they are and differences in food finding ability might be one of the factors that can explain this..
How does the KT Boost Fund support you and your project idea?
As an early-career researcher, it is crucial for me to develop into a truly independent scientist. This means that this is the ideal time to effectively show my ability to flexibly and successfully work on a variety of projects at any one time. Funding from the Klaus Tschira Boost Fund provides me with the opportunity to show exactly that, by allowing me, next to my current project (on bats), to also further explore an additional research project (on fish), which is independent of my current host institute and funding body.
If I had more time for things other than research I …
… would like to develop my creative skills. I love photography, making short science videos and designing pretty presentations. I would love to learn more about graphic design and how to reach people with creativity and humour. I would also like to spend more time volunteering in conservation projects, so I could use my scientific knowledge and skills to support conservation NGO’s. My dream is to help make this world a happier place, for people and animals.
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Name: Dr. Lysanne Snijders
Research field: Animal behaviour
Institution: Assistant Professor / NWO-Veni Fellow, Wageningen University Netherlands
Web: www.lysannesnijders.com
Twitter: @LysanneSnijders
LinkedIn: Dr Lysanne Snijders
Project Idea
UNESCO biosphere reserves aim to conserve biodiversity and satisfy human needs through ecosystem services, the beneficial contributions of ecosystems to people. For a better understanding of the relationship between biodiversity and ecosystem services it is crucial to analyse how ecosystem services are coproduced, i.e. how they result from biodiversity on the one hand and from human management on the other hand. The aim of BIOSHARE is to spatially analyse how ecosystem services are coproduced in different zones of biosphere reserves. The provisioning services crop production, grazing, and timber harvest, the regulating services soil fertility and pest control, and the cultural services recreation and landscape aesthetics will be studied.
How does the KT Boost Fund support you and your project idea?
The Klaus Tschira Boost Fund will be used to do exploratory and preparatory work to kick-start a larger, long-term research project led by the applicant. In particular, the funding will be used to 1) employ two research assistants to assist the applicant in building a global database containing information on biosphere reserve zoning, targeted ecosystem services and biodiversity in the respective biosphere reserves, and a geo-database containing land use intensity and ecosystem service data at different spatial resolutions, 2) organise a synthesis workshop with leading experts in the field, 3) fund two short research stays of the applicant and travel to initiate field studies.
If I had more time for things other than research I …
… would run more marathons, hike more day tours, have a bigger garden to grow even more of my own vegetables and start a bicycle workshop.
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Name: Dr. Matthias Schröter
Research field: Ecosystem services
Institution: Helmholtz Centre for Environmental Research – UFZ, Department of Computational Landscape Ecology
Web: www.ufz.de
Twitter: @MatthiasSchr
Project Idea
In applied disciplines contemporary data sets are often of increased size, detail and complexity. From a statistical point of view this is both a blessing and a curse imposing additional mathematical, computational and applied challenges to obtain realistic and reliable statistical models. In this project we want to combine the concepts of Bayesian regularization, machine learning and semi-and nonparametric methods to build efficient novel models that are extremely useful in the context of calibrated density regression. In contrast to classical statistical methods, Bayesian statistics offers a more direct expression of uncertainty through a prior distribution and allows updating knowledge.
How does the KT Boost Fund support you and your project idea?
During my assistant professorship, I have the goals to establish as an independent researcher with an international network of collaborations, to clearly improve my teaching skills and to grow into a successful group head, supervisor and mentor of the younger generation consisting of students, PhDs and postdoctoral researchers. The KT Boost Fund makes important contributions trough mentoring programmes and because it allows me to employ qualified scientific staff for reaching the project goals. I furthermore have the possibiliy to visit important conferences and collaboration partners in my field.
If I had more time for things other than research I …
… would learn Spanish properly, read more novels and travel more often to Australia.
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Name: Prof. Dr. Nadja Klein
Research field: Bayesian Computational Methods, Bayesian Deep Learning, Machine Learning, Smoothing, Regularization and Shrinkage, Distributional Regression, Network Analysis, Spatial Statistics
Institution: Humboldt University of Berlin, Assistant Professor of Applied Statistics at the Chair of Statistics
Web: www.wiwi.hu-berlin.de
Project Idea
Bone defects that commonly happened to 10-15% of fractures remained an unresolved clinical challenge. This project will utilize additive manufacturing, also known as 3D printing, for the possibility to produce scaffolds intended for bone regeneration with unprecedented structural and functional designs that could not otherwise be created. The scaffold is a porous structure made with absorbable polymers, i.e. plastic. In the initial phase, it is expected that the scaffold act as a temporary tissue expander to guide tissue in-growth and bone regeneration. Over time, the scaffold would be absorbed harmlessly by the body freeing space for new tissue formation. Ultimately, the bone defect will be completely healed with no traces of scaffold.
How does the KT Boost Fund support you and your project idea?
The KT Boost Fund provided me with the starting fund to performed experiments, which contribute towards my vision for “data-driven additive design and engineering” for the personalisation of bone regeneration. This made it possible for me to further strengthen existing collaborations. Additionally, as a member of KT fellow, I am given the opportunity to engage with the wider community to broaden my horizon, personally and professionally. The potential snow-ball effect would propel me towards becoming an accomplished scientist in STEM and hopefully become an inspirational role model for generations to come.
If I had more time for things other than research I …
… would travel the world! As a scientist, explorations is our nature. Venturing out of the lab to nature, experiencing the different culture and interactions with the people of various backgrounds gives me the opportunity to reflect and get inspired for the next sciency-ideas!
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Name: Dr. Patrina S.P. Poh
Research field: Bone Tissue Engineering, Additive Design and Manufacturing
Institution: Julius Wolff Institute, Charité – Universitätsmedizin Berlin
Web: ResearchGate; Julius Wolff Institute
Project Idea
Watching my German shorthaired pointer dog successfully recover from multiple hind limb surgeries in her old age led me to wonder how the body naturally copes with the healing process. In the mouse brain, my previous research also showed smooth recovery after a nerve crush that was aided by the very fast response and assistance of immune cells called macrophages. Such observations made me curious about the properties and functions of macrophages, and whether they remember what they have done the last time they were helpful. This project will allow me to follow individual macrophages as they carry out their task to rescue our organs after an injury.
How does the KT Boost Fund support you and your project idea?
The Klaus Tschira Boost Fund enables me to collaborate with outstanding junior scientists from world-class institutions while we establish our careers. Together with Dr. Franziska Denk (Wolfson Centre for Age-related Diseases, King’s College London) and Dr. Tristan Qingyun Li (Stanford University School of Medicine), I will investigate the activity and lifespan of macrophages in different types of brain injuries using sophisticated techniques for single-cell analyses. It is my great pleasure and honour to lead this study, through which we also aim to enhance international scientific cooperation. Furthermore, we share the common aspiration of promoting diversity and equality for women and minorities in science.
If I had more time for things other than research I …
… would follow up on our year-long podcast with a hilarious vlog starring Scarlet my three-legged dog!
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Name: Dr. Tuan Leng Tay
Research field: Neurobiology
Position: Assistant Professor in Biology and Anatomy & Neurobiology
Insitution: Boston University
Web: Boston University Profile; Loop
Twitter: @TayLab_CNS